Bills RB James Cook delivered 107 rushing yards and 2 TDs in Sunday's comeback win over New England. It's a major shock that Cook managed 22 carries, as the Bills fell behind 21-0 in the second quarter. The veteran RB also added a receiving score on 2 catches for 4 yards.

Colts QB Anthony Richardson has been medically cleared after fracturing his orbital bone on October 12, according to CBS Sports' Matt Zenitz. "The hope is to have him back practicing in the near future," Zenitz adds. Richardson has been out for over two months and isn't exactly what we'd call a polished player. So it might be asking too much to have him play again this season. His odds of getting back out there would probably improve if the Colts are eliminated from playoff contention. (They currently have just an 8% chance to make it, according to The Athletic's Playoff Predictor.) You could stash Richardson in deep 2-QB and superflex leagues, but don't drop anyone of value for him.

Seahawks WR Rashid Shaheed tallied 5 receptions for 74 yards on seven targets in Sunday's win over the Colts. All three numbers marked personal bests since he arrived in Seattle ahead of the Week 10 win over Arizona. Shaheed matched WR Cooper Kupp in targets and catches against Indy and beat him in yards. Both guys trailed WR Jaxon Smith-Njigba's lead in each category.

Seahawks QB Sam Darnold went without a TD pass for the third time in five games in Sunday's narrow victory over the Colts. He completed 22 of 36 throws (61.1%) for 271 yards (7.5 yards per attempt), with no TDs or INTs. With one game left to go in Week 15 as of this writing, his fantasy total sits 24th among QBs for the week by ESPN scoring. That will mark his fourth fantasy finish outside the top 20 among the past six weeks.

Packers WR Christian Watson did not suffer a "long-term injury" in Sunday's loss to the Broncos, ESPN's Rob Demovsky reports. Watson was taken to a local hospital for scans on his lungs, per Demovsky, but was able to fly home with the team. "His status for Saturday’s game against the Bears will be determined later in the week," Demovsky adds. It's all good news, but fantasy owners should at least be lining up an alternative plan for Week 16 fantasy lineups. We'll keep you updated on Watson's status throughout the week.

The Steelers have added RB Jaylen Warren to the injury report as questionable for tonight's game against the Dolphins with an illness. His absence would obviously give a large boost to Kenneth Gainwell and likely get rookie RB Kaleb Johnson more involved.

Cardinals RB Bam Knight suffered a "bad" ankle sprain in Sunday's loss to the Texans, according to ESPN's Adam Schefter. Knight is undergoing an MRI to get a better look at the damage. But he's "unlikely" to play vs. the Falcons this weekend, per Schefter. And it seems like there's a chance he misses the rest of the season. Knight's absence will leave Michael Carter as Arizona's lead back, with Emari Demercado in a change-of-pace, pass-catching role. Carter will be a viable RB3 or Flex in Week 16 fantasy lineups.

Cardinals TE Trey McBride posted a week-winning line in a Week 15 loss at Houston. On a 32.5% target share, the 26-year-old racked up 12 catches, 134 yards, and 2 TDs.

Lions RB Jahmyr Gibbs disappeared against the Rams despite the Lions scoring 34 points in the game. He went 13-38-0 on the ground and 4-20-0 through the air on 7 targets. His 9.8 PPR fantasy points were still more than teammate David Montgomery, who caught no passes in the game. Montgomery scored a TD, going 7-32-1 on the ground. The offense settled into QB Jared Goff’s hands, throwing the ball 41 times in the game.

Jaguars RB Travis Etienne lit up the score board going 3-73-3 through the air on 4 targets while struggling on the ground going 12-32-0. This comes with QB Trevor Lawrence throwing 5 TDs (and running for one more). Lawrence and Etienne led the Jaguars to 48 total points against the Jets as they continue fighting to win the AFC South.

Bengals QB Joe Burrow had one of the worst games of his career going 25/39 for 225 yards and 2 INTs with the Bengals scoring no points. This was the first time the Bengals have been shut out in a Burrow start. Despite the woeful offense, his weapons did come through in PPR with WR Ja’Marr Chase going 10-132-0 on 16 targets. RB Chase Brown went 13-53-0 on the ground but 7-37-0 through the air catching all of his targets.

Colts RB Jonathan Taylor survived with some fantasy value in Sunday's first game since the season-ending injury to QB Daniel Jones. Taylor ran for 87 yards on 25 carries and caught three of four targets for 14 more. Taylor's 3.5 yards per rush fell right in line with the 3.5 Seattle has allowed to the position for the season. Taylor's 13.1 PPR points marked the sixth-largest total for a QB against the Seahawks this season.

It's fun that the Colts almost upset the Seahawks in QB Philip Rivers' first game since 2020. But he certainly didn't boost the fantasy fortunes of anyone around him. Rivers completed a solid 18 of his 27 throws (66.7% completions) and found Josh Downs for an 8-yard TD. But he totaled just 120 yards (4.44 yards per attempt) and added an INT as well.

Before their Week 14 bye, it looked like the Carolina Panthers were shifting to a committee backfield with Rico Dowdle and Chuba Hubbard. But in Week 15, Dowdle out-carried Hubbard 16-8 and scored a TD to reclaim his status as Carolina's lead back. Neither back had much success against the Saints, who held the duo to a combined 3.25 yards per carry as New Orleans pulled off a 20-17 upset win.

Chiefs RB Isiah Pacheco reclaimed the rushing lead in Sunday's loss to the Chargers. He took his 11 carries for just 21 yards (1.9 per rush), while Kareem Hunt carried six times for 12 yards (2.0). Brashard Smith claimed the other two RB attempts, contributing a mere 1 yard. The usage pushed the backfield split back to what we saw from Kansas City backs before Pacheco's injury absence.

WR Ladd McConkey led the Chargers in pass routes in Sunday's win over the Chiefs, according to Pro Football Focus numbers. But that didn't equate to usable fantasy production. He managed just 2 receptions for 20 yards while trailing three teammates in targets. WR Keenan Allen led the team with seven targets and 5 receptions. Allen took those for just 36 yards, though. TE Oronde Gadsden and WR Tre Harris tied for second at five targets. Gadsden posted a 4-61 receiving line, ranking second on the team in catches and leading the way in receiving yards. Harris tallied 3 receptions for 49 yards.

RB Omarion Hampton led the Chargers in carries (15) and rushing yards (61) in Sunday's win over the Chiefs. He edged Kimani Vidal by three carries and matched his one target. But Hampton also trailed Vidal in playing time for the second straight week, powered by the Chargers favoring Vidal in passing situations. L.A. remained basically even in pass-run split, with 33 dropbacks vs. 29 designed run plays vs. Kansas City.

After a four-game slide where it appeared that Troy Franklin had lost his status as Denver's No. 2 WR, a hamstring injury suffered by Pat Bryant opened the door for Franklin to reassert himself as an integral part of Denver's passing attack. And he took advantage of the opportunity. Franklin caught all 6 of his targets for 85 yards and 1 TD in Denver's 34-26 win over the Green Bay Packers.

Texans HC DeMeco Ryans didn't sound concerned about RB Woody Marks' ankle injury after Sunday's win over the Cardinals. “Woody could’ve came back in the game," Ryans said. "But for where he was, got his ankle tweaked a little bit early in the game, for where he was, felt like Jawhar [Jordan] & Dare [Ogunbowale] were doing a really good job. So just wanted to keep rolling with those guys to make sure Woody is good as we continue to go into the week.” Marks' fantasy owners sure would have preferred he not sat out the final 2.5 quarters of the game. But it at least sounds like he has a chance to be ready for Week 16's meeting with the Raiders. We'll keep you posted on the rookie's status.

After being out-carried by Kyle Monangai in Chicago's last three games, D'Andre Swift reclaimed his No. 1 RB status in Week 15. Swift rushed 18 times for 98 yards and 2 TDs to help lead the Bears to a dominant 31-3 win over the Browns. Swift's 22.6 PPR points in this game were his second-highest total of the season.