ESPN's Adam Schefter reports that the Cardinals are "not optimistic" that WR Larry Fitzgerald will play today against the Rams. With Christian Kirk already on the COVID list, that would likely elevate Andy Isabella to the #3 WR spot behind DeAndre Hopkins and KeeSean Johnson. Isabella has been a healthy scratch the past 3 weeks. Arizona already gets a tough matchup vs. the Rams defense. Losing 2 of his normal top 3 WRs certainly doesn't help QB Kyler Murray.

On Friday, WR Larry Fitzgerald spoke about his NFL future on SiriusXM Mad Dog Sports Radio. “I just don’t have the urge to play right now,” Fitz said. “I don’t know how I’ll feel in September, October, November moving forward, but as of today I just don’t have the urge.” Currently a free agent, the 38-year-old was always believed to be leaning toward retirement. If that holds up, he'll retire with 1,432 career catches — 2nd most all-time.

NFL executives expect WR Larry Fitzgerald to retire at some point prior to the 2021 season, according to The Athletic's Mike Sando. Fitz has so far been hush-hush about his plans. He turns 38 in August and mustered just 7.6 yards per catch on 54 grabs last year. We've been anticipating this news: Fitzgerald isn't even in our 2021 WR rankings.

Cardinals WR Larry Fitzgerald (groin) is inactive for today’s game vs. the Rams. With WR Christian Kirk on the COVID list, Arizona is down to WRs DeAndre Hopkins, KeeSean Johnson and Andy Isabella.

Cardinals WR Larry Fitzgerald has been activated from the COVID list. He should step back in as Arizona's #3 WR against the Giants this weekend, pushing Andy Isabella back to 4th on the depth chart. Fitz has been a non-factor in fantasy this year, averaging 4.3 catches and 34 yards per game with 0 TDs.

Cardinals WR Larry Fitzgerald remains on the COVID list as of Friday afternoon and is unlikely to play against the Rams this weekend. With Fitz out last week, WR Andy Isabella played 56% of Arizona’s offensive snaps and saw 6 targets. He’s a WR4 play vs. a tough Rams pass defense.