Colts RB Jonathan Taylor (ankle) has been placed on IR, officially ending his 2022 season. RB Jordan Wilkins was signed to the active roster in a corresponding move. Wilkins joins Zack Moss and Deon Jackson in Indianapolis' backfield going forward. See where the Colts RBs sit in the initial Week 16 RB Rankings.

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Colts RB Jonathan Taylor has been diagnosed with a high-ankle sprain, according to NFL Network's Ian Rapoport. "He’s still meeting with doctors, but it’s considered highly unlikely that he’ll play again this season," Rapoport adds. Taylor was bothered by right ankle trouble all season and will end up missing 6 games and most of a 7th. Turning just 24 in January, he's an easy bounce-back candidate in 2023. We'll see what the Colts do at QB. Taylor's absence the rest of this season leaves the backfield to Zack Moss and Deon Jackson. Week 16 brings a solid matchup vs. the Chargers, but a bad Indianapolis offense and uncertain workload split will leave both guys as just RB3 or flex plays.

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ESPN's Adam Schefter reports that Colts RB Jonathan Taylor's latest ankle injury is considered "nothing major." Taylor is scheduled for additional testing, though. "And with the Colts 4-9-1 record, it is uncertain when or if he’ll play again this season," Schefter adds. We should learn more about Taylor's rest-of-season outlook over the next few days. The Colts deployed a 2-man committee backfield without Taylor for most of Saturday's loss to the Vikings, with Zack Moss handling 24 carries and 1 target and Deon Jackson tallying 13 carries and 1 target. Both guys will be low-end fantasy options if Taylor misses more time.

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Colts RB Zack Moss took advantage of RB Jonathan Taylor leaving Saturday's game early. He racked up 24 carries for 81 yards (3.4 per rush) in the OT loss to the Vikings. Moss also saw his lone target fall incomplete. We'll see about Taylor's status for a Week 16 home date with the Chargers. Moss will be worth grabbing on waivers in many cases ahead of that. RB Deon Jackson ran 2nd against Minnesota, carrying 13 times for 55 yards (4.2 per rush). He caught his lone target for 1 yard.

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