Comments: No Injury Status
Brandon Aiyuk's Injury Guide
Injury Risk
Chance of Injury in 2026
Chance of Injury per Game
Projected Games Missed 2026
Durability
Brandon Aiyuk's Injury Status
Current Status
Week 1 Practice Report
- Week Status:
- Active
- Likelihood of Playing:
- High
Brandon Aiyuk Injury History
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| Date | League | Injury | Level | Games Missed | Details |
|---|---|---|---|---|---|
| Oct 20, 2024 | NFL | Knee ACL Tear | Grade 3 | 27 | Aiyuk tore his ACL and MCL in the second quarter of Week 7's game vs. the Chiefs. UPDATE: On November 21, 2025, the 49ers voided Aiyuk's guaranteed money for lack of participation. |
| Sep 17, 2023 | NFL | Shoulder | — | 1 | Aiyuk reportedly sustained the injury in the first quarter of Week 2 vs. the Rams, though he played through in that contest. He subsequently missed Week 3 vs. the Giants. |
| Aug 27, 2021 | NFL | Thigh Hamstring Sprain/Pull | Grade 1 | — | Aiyuk picked up a minor hamstring injury that kept him out of the 49ers' preseason finale. |
| Dec 26, 2020 | NFL | Pedal Ankle (high) Sprain | Grade 3 | 1 | Aiyuk suffered a high-ankle sprain in Week 16 game against the Arizona Cardinals. He missed the season finale game against the Seattle Seahawks. |
| Aug 23, 2020 | NFL | Thigh Hamstring Strain | Grade 2 | 1 | Aiyuk left the training camp practice due to an apparent hamstring injury. He missed the season opener against the Cardinals |
| Apr 7, 2020 | Non-NFL | Inguinal Groin Sports | — | — | Aiyuk underwent a core-muscle surgery as he has dealt with the issue for a few months. |
Brandon Aiyuk Injury News
View AllBrandon Aiyuk Placed On PUP List
The San Francisco 49ers have placed WR Brandon Aiyuk on the PUP list, according to Adam Schefter of ESPN. He’ll miss at least the four weeks of the season.
Is Brandon Aiyuk About to Miss a Third of the Season (or More)?
Niners HC Kyle Shanahan told reporters Monday that all the team's "ACL guys" -- in the words of The Athletic's Matt Barrows -- are on track to return around Week 6. That includes WR Brandon Aiyuk, of course.
Brandon Aiyuk Unlikely to be Cleared for Week 1, Opening Up WR Opportunities
49ers GM John Lynch stated that he "doesn't think" WR Brandon Aiyuk will be cleared for Week 1. Aiyuk tore his ACL and MCL last October in Week 7. Week 1 will mark a little over 10 months since sustaining the injury. There has been no official timeline laid out by the team for Aiyuk's return.