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| Date | League | Injury | Level | Games Missed | Details |
|---|---|---|---|---|---|
| Jan 11, 2026 | Non-NFL | Pedal Achilles Tear | Grade 3 | 1 | Kittle tore his right Achilles in the second quarter of San Francisco's Wild Card playoff game in Philadelphia. |
| Dec 22, 2025 | NFL | Pedal Ankle Sprain | Grade 2 | 1 | George Kittle sustained a left ankle sprain during the Week 16 game against the Indianapolis Colts. |
| Sep 7, 2025 | NFL | Thigh Hamstring Tear | Grade 3 | 5 | Kittle suffered a hamstring injury during the 49ers' Week 1 game against the Seahawks. |
| Nov 10, 2024 | NFL | Thigh Hamstring Sprain/Pull | Grade 1 | 1 | Kittle missed Week 11 with a hamstring injury. This was the second time in the 2024 season that he missed a game due to a hamstring injury. |
| Sep 15, 2024 | NFL | Thigh Hamstring Sprain/Pull | Grade 1 | 1 | Kittle missed Week 3 with a hamstring injury |
| Nov 12, 2023 | NFL | Inguinal Groin Sports | — | — | Kittle played through the injury and then underwent offseason surgery. |
| Aug 9, 2023 | NFL | Inguinal Groin Pull | Grade 1 | — | Kittle is expected to miss about one week of practice |
| Sep 5, 2022 | NFL | Inguinal Groin Strain | Grade 2 | 2 | Kittle missed the first 2 games. |
| Dec 15, 2021 | NFL | Knee Strain | Grade 1 | — | Kittle dealt with a knee soreness ahead of the Week 15 game against Atlanta. |
| Sep 26, 2021 | NFL | Leg Calf Strain | — | 3 | Kittle emerged from the 49ers' Week 3 loss to the Packers with a calf injury. He played through it in the next game before being placed on IR. |
| Nov 1, 2020 | NFL | Pedal Foot Fracture | — | 6 | Kittle suffered a small fracture in his foot during Week 8's loss to the Seahawks. He was placed on IR |
| Sep 13, 2020 | NFL | Knee MCL Sprain | Grade 2 | 2 | Kittle was diagnosed with a sprained left knee in the wake of Week 1's loss to the Cardinals. He missed two games |
| Aug 27, 2020 | NFL | Thigh Hamstring Strain | Grade 2 | — | Kittle dealt with a tight hamstring during the training camp |
| Oct 31, 2019 | NFL | Knee Patella Sprain | — | 2 | Kittle suffered an injury to his knee in Week 9 game vs. the Cardinals. He missed two games |
| Aug 9, 2018 | NFL | Shoulder A/C Joint Separation | — | — | Kittle separated his right shoulder in the preseason opener. There was no structural damage. |
| Nov 5, 2017 | NFL | Pedal Ankle Sprain/Pull | Grade 1 | 1 | Kittle missed 1 game with a sprained ankle. |
| Aug 1, 2017 | NFL | Thigh Hamstring Sprain/Pull | Grade 1 | — | Kittle missed about a week of training camp with a hamstring injury. He was ready for Week 1. |
| Oct 15, 2016 | Non-NFL | Pedal Foot Sprain | — | 2 | Kittle injured his right foot against Purdue on October 15. He was limited the rest of the season and missed 2 games. |
Several reports have 49ers TE George Kittle missing multiple weeks with the hamstring injury he suffered in Sunday's win over the Seahawks. NFL Network's Ian Rapoport reports it'll likely be 3-5 weeks. His absence means more playing time for TEs Luke Farrell and Jake Tonges, but neither makes for an attractive addition in fantasy leagues right now. We'll see whether Kittle lands on IR, which would tell us more about his return timeline.
The San Francisco 49ers have placed WR Brandon Aiyuk on the PUP list, according to Adam Schefter of ESPN. He’ll miss at least the four weeks of the season.
Niners HC Kyle Shanahan told reporters Monday that all the team's "ACL guys" -- in the words of The Athletic's Matt Barrows -- are on track to return around Week 6. That includes WR Brandon Aiyuk, of course.
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