The Colts went without several defensive starters in Wednesday's practice. LB Darius Leonard (ankle), DE Kwity Paye (hamstring), S Khari Willis (ankle, groin) and CB Rock Ya-Sin (ankle) all missed the workout. Leonard sustained his injury last week and missed Thursday's practice before playing through it at Tennessee. The other 3 left Sunday's game early. We'll see about the progress for each throughout the week.

Colts DT DeForest Buckner and CB Kenny Moore are both active for today's game against the Jaguars. Each player turned up questionable with a hip injury but is in play for IDP lineups.

The Colts have activated DE Tyquan Lewis and S Rodney McLeod from the physically unable to perform list. Each guy has been working back from a knee issue, and it appears each is now ready for regular training camp participation.

The Colts have activated DT DeForest Buckner and DL Denico Autry off the COVID list. Both starters missed last week's game against the Titans, helping RB Derrick Henry to a huge rushing day. David Johnson -- assuming he's activated from IR in time -- won't be so fortunate in this Sunday's matchup. Both Buckner and Autry belong in IDP consideration for Week 13. Check our IDP rankings to see whether you should be starting either guy.

Colts LB Anthony Walker (ribs) and S Khari Willis (ribs, shoulder) are active for today's game against the Titans. Neither is a high-level IDP option, but they're in play for deeper leagues. Walker should gain playing time with LB Bobby Okereke out (ankle).

The Colts have ruled LB Bobby Okereke (ankle) out for Sunday's game against the Titans. LB Anthony Walker (ribs) and S Khari Willis (ribs, shoulder) are questionable. We'll update their status Sunday morning.