Packers OLB Nick Perry (knee), S Kentrell Brice (ankle) and CB Kevin King (hamstring) will not travel to Seattle for Thursday night's game, according to ESPN's Rob Demovsky. That will leave the defense without 3 starters against a solid Seattle offense. Green Bay already sits outside the top 12 of our Week 11 team-D rankings.

Packers OLB Nick Perry is active for today's game against the Bills. That means he cleared the league concussion protocol over the weekend, despite putting in just a single limited practice Friday. Perry makes for an upside play in sack-friendly IDP leagues in a matchup that should find Buffalo playing from behind.

Packers DE Muhammad Wilkerson suffered a "significant" ankle injury in Sunday's game at Washington, HC Mike McCarthy told reporters Monday. The injury required Wilkerson to have an unspecified procedure on the ankle before he could travel back to Green Bay. We'll await further word on the injury, but it sure sounds like this will end Wilkerson's season. McCarthy also revealed Monday that OLB Nick Perry has entered the league concussion protocol. He'll need to clear that before playing in an upside sack matchup against the Bills on Sunday.

Update: ESPN's Rob Demovsky reports that Wilkerson's season is over.

Packers OLB Nick Perry (foot) and ILB Jake Ryan (knee) are active for today’s game against the Panthers. Perry put in limited practices all week after missing last week’s workouts and then sitting out the game. Ryan missed Wednesday’s practice before limited workouts Thursday and Friday. Each player adds risk to his already lower-level IDP profile with the injury status.

Packers OLB Nick Perry (foot) is inactive for today's game against the Browns. That removes the sack leader from a shaky Green Bay pass rush. The Packers remain an upside play on D, though the recent additions at WR and spotty rushing success add scoring risk to the Browns offense.

The Packers have ruled DE Mike Daniels (hip) and OLB Nick Perry (hand) doubtful for Sunday's game against the Bengals.

Packers OLB Nick Perry is active for today's game against the Vikings after losing the past 2 weeks to a hand injury. His return helps the pass rush and adds upside to a sneaky team-defense play for fantasy owners. CB Damarious Randall (shoulder) is also active after entering the weekend questionable.

Packers ILB Blake Martinez (knee) is questionable for Sunday's game against the Bears. He put in limited practices all week but has since Week 13. Martinez makes for a weak IDP option at this point, even if active. We'll check on his status Sunday, though. OLB Nick Perry (hand) is doubtful. CB Damarious Randall (groin) is questionable.

The Packers have ruled OLB Nick Perry out for Sunday's game against the Seahawks with what HC Mike McCarthy deemed a "significant hand injury," according to The Associated Press. It's not a huge loss for IDP owners but does take arguably the team's top current pass rusher off the field.

Packers OLBs Mike Neal and Nick Perry each sat out Friday's practice, but the Milwaukee Journal-Sentinel reports that both will play against the Niners on Sunday.  Both players have been dealing with injuries that have kept them from putting in a full padded practice for more than 2 months.  They'll be integral to containing 49ers QB Colin Kaepernick, but the weak Packers D looks like a poor bet to hold down San Francisco even with Neal and Perry.

The Green Bay Press-Gazette posits that 1st-round pick Nick Perry "figures to start right away" at ROLB. GM Ted Thompson said he likes Perry's ability to set the edge against the run and rush the passer. That sounds like a starter and full-timer. Perry delivered a Pac-12 best 9.5 sacks last year. We'll see how his pass-rush ability translates from 4-3 LE in college to 3-4 OLB in the NFL. Perry is worth a late shot in IDP leagues that are less tackle heavy.