The Titans have ruled RB Dontrell Hilliard (hamstring) out for Monday night's game against the Bills. That should position rookie Hassan Haskins as the #2 RB, though Trenton Cannon and Julius Chestnut could factor in as well. None is likely to get enough touches to be fantasy relevant.

49ers RB Trey Sermon (concussion) has been medically cleared and isn't listed on the final injury report. With RB JaMycal Hasty (ankle) out and RB Elijah Mitchell (shoulder) doubtful, it's currently Sermon, Trenton Cannon and Jacques Patrick at RB on San Francisco's active roster. RBs Kerryon Johnson and Chris Thompson are eligible to be activated from the practice squad. HC Kyle Shanahan wouldn't say Friday afternoon who will get the start vs. Green Bay, but multiple 49ers beat writers expect it to be Sermon. We'll continue to look for clues on how the touches will be divvied.

49ers GM John Lynch called RB Elijah Mitchell (shoulder) "very questionable" for Sunday night's game against the Packers. We'll see if Mitchell does anything in practice later today -- and then how he's listed on the final injury report. RB Trey Sermon's Week 3 status is also up in the air with his concussion. Trenton Cannon and Jacques Patrick are the only healthy RBs on San Francisco's active roster. RB Kerryon Johnson is a potential practice-squad callup.

Niners HC Kyle Shanahan said Wednesday that he hoped RB Elijah Mitchell's shoulder injury was merely a stinger but that it's actually a "little worse," according to Eric Branch of the San Francisco Chronicle. "He's got a chance" to play in Week 3, Shanahan added. We'll have to track Mitchell's progress through the week. The other injuries around the San Francisco backfield make it tough to know right now what the succession plan would be if Mitchell's out.

The 49ers on Wednesday claimed RB Trenton Cannon off waivers from the Ravens. He joins a depth chart that also includes Elijah Mitchell, Trey Sermon and JaMycal Hasty -- in some order -- plus Kerryon Johnson, a recent addition to the practice squad. We'll see where all this goes.

The Ravens won't be activating RB Le'Veon Bell or Devonta Freeman from the practice squad ahead of tonight's game against the Raiders. They instead elevated CB Anthony Levine Sr. and DL Justin Ellis to help cover injuries at those positions. That leaves Ty'Son Williams as the expected lead back vs. Vegas, with Latavius Murray and Trenton Cannon behind him.

An MRI confirmed a torn ACL for Ravens RB Gus Edwards, ESPN's Adam Schefter reports. So Edwards, like teammates J.K. Dobbins and Justice Hill, will miss the entire 2021 season. That leaves Baltimore with RBs Ty'Son Williams and Trenton Cannon on the active roster and RBs Le'Veon Bell and Devonta Freeman on the practice squad. Williams is a good bet to lead the way in Monday night's opener vs. the Raiders. We'll see where the backfield goes beyond that.

The Ravens have signed RB Devonta Freeman to their practice squad. "The idea is that Freeman will be promoted to Ravens’ active roster," ESPN's Adam Schefter tweeted. It's unclear when Freeman will be ready to join the active roster. He joins Le'Veon Bell on Baltimore's practice squad, with Ty'Son Williams and Trenton Cannon on the active roster. There's a lot of settling that needs to happen in this backfield. In the short term, Williams is the best fantasy bet.

Ravens RB Gus Edwards left practice Thursday after suffering a "potentially serious" knee injury, according to NFL Network's Ian Rapoport. ESPN's Adam Schefter reports that the team fears he tore an ACL. Baltimore actually cut the practice short after Edwards and CB Marcus Peters injured knees on consecutive plays. Both are heading in for testing, and we'll certainly keep watch for updates. If the testing confirms that fear, Edwards would be the 3rd RB the Ravens have lost for the season, following J.K. Dobbins (ACL) and Justice Hill (Achilles'). That would leave Ty'Son Williams and Le'Veon Bell to potentially lead the backfield in Week 1 and beyond. Baltimore also recently signed RB Trenton Cannon, but he's more of a special-teamer. Grabbing Bell off waivers where possible suddenly seems like a solid plan.

The Ravens have signed RB Trenton Cannon to the active roster. That comes at the same time as the team added Le'Veon Bell to the practice squad, which should answer your question if you're wondering whether to claim Bell off waivers. Cannon has 48 career carries and 28 targets since hitting the league as a 6th-round pick of the Jets in 2018. He's expected to primarily contribute on special teams.