Zak Keefer of The Athletic reports that Colts LB Shaquille Leonard and DL Tyquan Lewis will miss Thursday's game against the Broncos because of concussions they suffered in Sunday's loss to the Titans. We'll see about the availability of both players for Week 6 (vs. Jacksonville).

The Colts have activated DE Tyquan Lewis and S Rodney McLeod from the physically unable to perform list. Each guy has been working back from a knee issue, and it appears each is now ready for regular training camp participation.

The Colts have placed LB Darius Leonard on the PUP list to open training camp. It's not a surprise. Leonard had back surgery in early June, and it was reported at the time that he'd miss some of camp. Lingering trouble with the ankle that has been bothering Leonard since before last season started might be the bigger concern, though. We'll see how long the star remains on the PUP list, from which the team can activate him at any time. If Leonard winds up on the regular-season PUP list, he'd have to miss at least 4 games. To date, we haven't seen that reported as a possibility. The Colts also placed S Rodney McLeod (undisclosed) and DE Tyquan Lewis (knee) on the PUP ahead of camp starting.

The Colts picked up Ohio State DE Tyquan Lewis after trading up to the final spot in Round 2 of the NFL Draft. Lewis delivered a 91st-percentile SPARQ score in predraft testing after tallying 23 sacks over his final 3 college seasons. Lewis figures to be a rotational player with the Colts, though, and will turn 24 before the end of his rookie season.