The Cardinals will keep QB Kyler Murray on the physically unable to perform list to open the regular season, according to multiple reports. That's no surprise, as Murray continues to work back from a November ACL tear. He'll miss at least the first four games. We've had Murray projected to miss five games all along in your fantasy football rankings. The Cardinals are also releasing QB Colt McCoy. That'll mean it's either rookie Clayton Tune or newly acquired Josh Dobbs starting for Arizona over the first month. We'll see who wins that post between now and Week 1.

Cardinals QB Kyler Murray tallied 214 yards and one score passing and 51 yards and another TD rushing in the Week 11 loss to the Texans. The passing performance left plenty to be desired. Murray averaged a decent 7.1 yards per attempt but had a handful of misfires, including underthrowing WR Marquise Brown on a potential long TD. But Murray was again active and productive as a runner. He's now totaled 13 carries, 84 yards, and two TDs over the last two weeks. That will keep him in the lower-end QB1 mix going forward, with upside beyond that if he settles in as a passer. Murray gets neutral matchups the next two weeks vs. the Rams and Steelers before a Week 14 bye.

Cardinals HC Jonathan Gannon officially named QB Kyler Murray the Week 10 starter on Friday. Sunday's game vs. the Falcons will mark Murray's first action since tearing his ACL last December. His rushing figures to be curtailed coming off that knee injury. And remember that this will be Murray's first game in OC Drew Petzing's offense. He'd be a risky QB1 fantasy play in Week 10 but could quickly work his way into the top-12 discussion.

Cardinals HC Jonathan Gannon said Monday that QB Kyler Murray will start Sunday against the Falcons, assuming he has another good week at practice, according to Darren Urban of the team website. This has been the expected return date for weeks now, despite Murray rejoining practices in Week 7. Arizona's caution and patience in bringing Murray back from his ACL tear should mean we get something close to a full-strength version. Of course, we can't know how often or how effectively Murray will run until we see him in games. His return can only help a passing game, though, that got just 58 yards, 2 INTs and 7 sacks from rookie Clayton Tune in Sunday's shutout loss to Cleveland. We're hoping for Murray to bring top-12 fantasy upside among QBs. We're betting on him enhancing the fantasy outlooks for other Arizona skill-position players.

Update: The Cardinals officially activated Murray from the PUP list on Tuesday.

Cardinals QB Kyler Murray (knee) was not activated to the 53-man roster and is out for Sunday's game vs. the Browns. He's been a full-go in practice the past two weeks. We're expecting Murray to make his 2023 debut next weekend. Rookie QB Clayton Tune will make his first career start tomorrow.

Cardinals QB Kyler Murray (knee) is officially questionable for Sunday’s game vs. the Browns. He was listed as doubtful last week. HC Jonathan Gannon wouldn’t say Friday who will start at QB this weekend. We’re still expecting it to be Clayton Tune but will keep you updated on the situation.