The Giants have officially ruled RB Saquon Barkley out for Thursday night's game against the 49ers. That's been expected since news broke of his Week 2 ankle sprain. Matt Breida is expected to be the first guy up in the Week 3 backfield, but that's only enough to land him in RB4 territory in our Week 3 RB rankings. Expect Gary Brightwell and rookie Eric Gray to mix in as well for a backfield that has been limited even with Barkley through two weeks.

The Giants' offense has struggled lately but managed to support a big game for RB Saquon Barkley in Sunday's win over the Commanders. Barkley rushed 14 times for 83 yards (5.9) per rush and added a 4-57-2 receiving line on 5 targets. That tied him for the team high in targets and marked Barkley's most receptions in a game since Week 6. The yardage was a season high. Playing a lackluster Washington defense certainly helped. The Giants get a neutral matchup with New England in Week 12 before a Week 13 bye. After that comes a positive matchup for RB scoring with Green Bay, but three straight negative matchups to finish the season. That makes Barkley a potential sell if your trade deadline hasn't passed yet. Barkley's receiving ability helps him in negative matchups, though, so he can certainly remain useful in fantasy. Barkley has also topped 5.0 yards per carry in three straight contests.

Giants RB Saquon Barkley recorded 13 carries for 66 rushing yards with 1 catch for -5 yards in Week 10 vs. the Cowboys. Fantasy managers expected tough sledding against a fierce Cowboys defense, and there’s no sugarcoating a 7.1 PPR point performance. The moribund offense will hurt Barkley the rest of the way, and the Giants’ remaining schedule ranks as the toughest for RBs per our adjusted fantasy points allowed. You might get flex-level value from Barkley on volume, but keep your expectations low.

RB Saquon Barkley essentially served as the Giants’ entire offense in Week 8 vs. the Jets, totaling 36 carries for 128 rushing yards with 3 catches. The team had to pivot early on after starting QB Tyrod Taylor (ribs) and TE Darren Waller (hamstring) left in the second quarter due to injury and settled on pounding the rock all the way through OT. It’s difficult to draw any meaningful fantasy-based conclusions from this game due to the dire circumstances. Keep an eye on the practice reports this coming week to see who’ll be available to suit up vs. the Raiders in Week 9.

Giants RB Saquon Barkley (elbow) is not listed on the final Week 8 injury report. He hyperextended his elbow last week but returned to that game and will be ready for a full workload vs. the Jets on Sunday.

Giants RB Saquon Barkley (elbow) was limited in Wednesday's practice. He was able to play through the hyperextended elbow last week and should be fine for Sunday's game vs. the Jets.