49ers WR Brandon Aiyuk (shoulder) remained limited in Thursday's practice but was out of his non-contact jersey, according to The Athletic's David Lombardi. Aiyuk is trending toward returning for this weekend's game vs. the Cardinals. We'll see how he's listed on the final injury report tomorrow.

49ers WR Brandon Aiyuk (shoulder) was limited in Wednesday's practice. He was seemingly close to playing last Thursday night, so we're tentatively expecting him back for this weekend's game vs. the Cardinals.

49ers WR Brandon Aiyuk (shoulder) is officially inactive for tonight's game vs. the Giants. He seemed relatively close to playing tonight, so we're tentatively expecting him back for Week 4. Aiyuk's absence should make San Francisco's offense even more concentrated, with RB Christian McCaffrey, WR Deebo Samuel, and TE George Kittle dominating touches.

The 49ers have downgraded WR Brandon Aiyuk to out for tonight's game against the Giants because of his shoulder injury. That should make Jauan Jennings the No. 2 WR for the upside matchup. Aiyuk (14) and Deebo Samuel (16) have accounted for 88.2% of WR targets for San Francisco through two weeks, with Jennings claiming the only other four. Jennings posted three games of 4+ receptions last year, though none came with Brock Purdy behind center. Jennings makes for a nice play in Thursday night DFS showdowns. He's too much of a longshot for most season-long redraft formats, though. Seventh-round rookie Ronnie Bell has been the No. 4 WR in playing time so far and matched Jennings in snaps in Week 2. He has yet to see a target, though.

The 49ers list WR Brandon Aiyuk (shoulder) as questionable for Thursday night's game against the Giants. ESPN's Nick Wagoner reports that HC Kyle Shanahan "indicated" Aiyuk will be a game-time decision. Fortunately, it's the first game of the week. So we'll know more before you're setting your Week 3 lineups.

49ers WR Brandon Aiyuk (shoulder) will be a game-time decision for Thursday night's meeting with the Giants, HC Kyle Shanahan said Tuesday. Aiyuk was limited in Tuesday's practice. We'll continue to look for updates on his status, but it seems like he'll come with elevated risk in Week 3 fantasy lineups if he does suit up on Thursday night.

A CT scan on 49ers WR Brandon Aiyuk's clavicle came back clean, according to The Santa Rosa Press Democrat's Jack Hammer. "His ability to play Thursday night will be all about pain tolerance," Hammer adds. We'll keep an eye on Aiyuk's status and will get San Francisco's inactives around 7 pm ET on Thursday.

49ers WR Brandon Aiyuk injured his left shoulder on the opening drive of Sunday's win over the Rams. He eventually returned to the game but ended up playing just 53% of the offensive snaps. HC Kyle Shanahan on Monday wouldn't commit to Aiyuk being available for Thursday night's game vs. the Giants. We're tentatively expecting Aiyuk to be out there for that one, but we'll watch his status over the next few days.

49ers WR Brandon Aiyuk exploded in Week 1 vs. the Steelers, hauling in all 8 targets for 129 receiving yards and 2 TDs. Teammate Deebo Samuel logged 5 catches on 7 targets for 55 of his own, and yards TE George Kittle had a quiet contest with just 3 catches on 6 targets for 19 yards. Despite the best efforts of Steelers CB Patrick Peterson, Aiyuk could not be stopped en route to setting a new career-high in yards in Sunday’s win. As a whole, the 49ers’ offense fired on all cylinders. Next week, the 49ers will face off against the Rams, a division opponent they beat in both of their matchups last season.

The Athletic's David Lombardi writes that 49ers WR Brandon Aiyuk “continues dominating” at training camp. Aiyuk brings undeniable talent, and he should be hitting his prime at 25 years old. Volume looks like an issue, though. And we’ll have to see how QB Brock Purdy performs in live action following March elbow surgery.

49ers WR Brandon Aiyuk is coming off a top-25 finish among WRs in fantasy points per game and has had an impressive offseason by all accounts. But his target volume is a concern heading into 2023. Aiyuk drew a 22.0% target share last year -- 32nd among WRs. But that dipped to 20.1% in 14 games with a healthy WR Deebo Samuel. Aiyuk saw just 17.9% of 49ers targets in seven games with Samuel and RB Christian McCaffrey. Samuel, McCaffrey, and TE George Kittle are back this year. And San Francisco figures to remain a run-leaning offense regardless of who's playing QB. That has Aiyuk sitting a bit lower in the WR Rankings than his talent would dictate.

49ers WR Deebo Samuel led the team in receiving with 6 catches on 9 targets for 133 yards and 1 TD in Saturday's Wild Card win vs. the Seahawks. The crafty wideout also handled 3 carries for 22 yards on the ground in the contest. Samuel was seldom used in Week 18 after returning from a 3-game absence due to injury, so it's good to see his body hold up to a more significant workload. It's also worth noting that teammate WR Brandon Aiyuk is the only other 49ers' pass-catcher who logged more than 2 receptions.

Niners TE George Kittle tallied 6 catches for 120 yards and 2 TDs in Saturday's win over the Commanders. Kittle led his team in all 3 categories. It marked his 2nd straight 2-TD game. WR Brandon Aiyuk followed with 5 catches for 81 yards on 7 targets. WR Jauan Jennings (2) and RB Christian McCaffrey (2) were the only other 49ers to catch passes. San Francisco gets an upside matchup with the Raiders in Week 17.

49ers WR Deebo Samuel (ankle, knee) is out for Thursday night's game vs. the Seahawks. It sounds like he'll be back in either Week 17 or 18. Samuel's absence elevates Jauan Jennings to the #2 WR role and frees up targets for RB Christian McCaffrey, WR Brandon Aiyuk and TE George Kittle.

49ers WR Deebo Samuel suffered an MCL sprain and an ankle sprain in Sunday's win over the Bucs, the team announced on Monday. Samuel is expected to return at some point in the regular season, but we'd prepare for him to miss multiple games. We'll hopefully get a more concrete timeline for Samuel's return before you need to decide whether to release him from fantasy rosters. Jauan Jennings will take over as San Francisco's #2 WR with Samuel out but is unlikely to be a reliable fantasy play at this point in the season. RB Christian McCaffrey, WR Brandon Aiyuk and TE George Kittle are all candidates to pick up extra targets with Samuel out.

49ers QB Jimmy Garoppolo does not have a Lisfranc injury and won't need surgery, ESPN's Adam Schefter reports. Garoppolo could be back in 7-8 weeks, "if rehab goes smoothly," Schefter adds. Seven weeks would put Garoppolo back on the field for the Divisional Round of the playoffs. We'll keep an eye on his progress. Garoppolo is still a guy to avoid in playoff fantasy contests, but this news helps the outlooks on San Francisco's skill-position players.