Niners TE George Kittle tallied 6 catches for 120 yards and 2 TDs in Saturday's win over the Commanders. Kittle led his team in all 3 categories. It marked his 2nd straight 2-TD game. WR Brandon Aiyuk followed with 5 catches for 81 yards on 7 targets. WR Jauan Jennings (2) and RB Christian McCaffrey (2) were the only other 49ers to catch passes. San Francisco gets an upside matchup with the Raiders in Week 17.

49ers WR Deebo Samuel (ankle, knee) is out for Thursday night's game vs. the Seahawks. It sounds like he'll be back in either Week 17 or 18. Samuel's absence elevates Jauan Jennings to the #2 WR role and frees up targets for RB Christian McCaffrey, WR Brandon Aiyuk and TE George Kittle.

49ers WR Deebo Samuel suffered an MCL sprain and an ankle sprain in Sunday's win over the Bucs, the team announced on Monday. Samuel is expected to return at some point in the regular season, but we'd prepare for him to miss multiple games. We'll hopefully get a more concrete timeline for Samuel's return before you need to decide whether to release him from fantasy rosters. Jauan Jennings will take over as San Francisco's #2 WR with Samuel out but is unlikely to be a reliable fantasy play at this point in the season. RB Christian McCaffrey, WR Brandon Aiyuk and TE George Kittle are all candidates to pick up extra targets with Samuel out.

WR Jauan Jennings led the 49ers with 6 catches in Sunday's win over the Saints, taking them for 49 yards and the team's lone TD. Jennings' 7 targets tied Deebo Samuel for 2nd on the team, trailing only WR Brandon Aiyuk. Samuel caught 3 balls for 43 yards, adding 2 carries for no gain. Aiyuk caught 5 passes for 65 yards. TE George Kittle contributed 3 receptions for 26 yards on 4 targets.

Niners WR Brandon Aiyuk drew a team-high 7 targets in Sunday night's win over the Chargers, also leading the team in receptions (6) and receiving yards (84). WR Deebo Samuel trailed by just 1 target but caught only 2 passes for 24 yards. Samuel hasn't beaten Aiyuk in targets since Week 5. TE George Kittle managed just 1 reception for 21 yards among 2 targets. WR Jahan Jennings caught all 4 of his looks for 40 yards. The 49ers head to Mexico City next Monday night to face the Cardinals.

49ers WR Jauan Jennings (hamstring) is inactive for today’s game vs. the Rams. He joins WR Deebo Samuel on the sidelines for this one, leaving WRs Ray-Ray McCloud, Danny Gray and Willie Snead behind Brandon Aiyuk.

49ers WR Deebo Samuel (hamstring) has been ruled out for Sunday’s game vs. the Rams. He leaves behind 7.7 targets per game, which should mostly be absorbed by WR Brandon Aiyuk, TE George Kittle and RB Christian McCaffrey. San Francisco could also lean on the running game more with Samuel out. WR Jauan Jennings (hamstring) is listed as questionable for Sunday’s game.

49ers WR Deebo Samuel (hamstring) remained sidelined for Thursday's practice. He's in danger of missing this weekend's game vs. the Rams. We'll see if Samuel practices Friday and how he's listed on the final injury report. WR Jauan Jennings (hamstring) also missed practice again on Thursday.

49ers WR Deebo Samuel (hamstring) did not practice on Wednesday. HC Kyle Shanahan labeled Samuel "day to day" on Monday, but his availability for this weekend's game vs. the Rams is in question. WR Jauan Jennings (hamstring) also missed Wednesday's practice. We'll get another update on both guys tomorrow.

Niners WR Deebo Samuel fulfilled the Deebo Samuel role in Sunday's opening loss to the Bears. He drew a team-high 8 targets but caught just 2 for 14 yards in rain-drenched conditions. Samuel added 52 yards and a TD on 8 carries, trailing only QB Trey Lance among 49ers in rushing yards. We certainly can't count on rushing scores every week for Samuel, but the target count to go with the rushing work is encouraging. That's what lacked in the 2nd half of last year, when he was getting more handoffs than passing looks. Brandon Aiyuk drew just 2 target against the Bears, catching both for 40 yards. WR Jauan Jennings posted team highs of 4 receptions and 62 yards on 6 targets.