The Cardinals will keep QB Kyler Murray on the physically unable to perform list to open the regular season, according to multiple reports. That's no surprise, as Murray continues to work back from a November ACL tear. He'll miss at least the first four games. We've had Murray projected to miss five games all along in your fantasy football rankings. The Cardinals are also releasing QB Colt McCoy. That'll mean it's either rookie Clayton Tune or newly acquired Josh Dobbs starting for Arizona over the first month. We'll see who wins that post between now and Week 1.

The Cardinals acquired QB Joshua Dobbs and a 2024 seventh-round pick from the Browns in exchange for a 2024 fifth-rounder. Dobbs joins Colt McCoy and Clayton Tune as the healthy QBs in Arizona. The Cardinals have yet to name a Week 1 starter, with QB Kyler Murray still on the mend. The Browns, meanwhile, look set to roll with rookie QB Dorian Thompson-Robinson as QB Deshaun Watson's backup.

The Cardinals are placing QB Kyler Murray on the PUP list to open training camp, to the surprise of absolutely no one. Murray, of course, is working back from a Dec. 12 ACL tear. The main question on him for 2023 has been just how much regular-season time he'll miss. We'll continue watching for more insight on that.

Cardinals HC Kliff Kingsbury conceded Wednesday that QB Kyler Murray (knee) "probably" won't be ready for the start of the 2023 season. Murray underwent surgery Tuesday to reconstruct his ACL and repair meniscus damage in his right knee. We're just about 8 months from the start of the 2023 campaign; this is an injury that usually takes 9+ months to return from. Early fantasy drafters should be operating under the assumption that Murray misses at least the first few games. The PUP list, which would cost him the first 6 games, is a real possibility. Kingsbury also said that QB Colt McCoy isn't playing this weekend to protect him from injury, suggesting that he might be Plan A to replace Murray early next season. McCoy is signed for 2023 with a reasonable $5 million cap hit.

Cardinals QB Colt McCoy had his concussion symptoms return Friday and will not play Sunday against the Falcons, HC Kliff Kingsbury told reporters. The team will instead turn to QB David Blough for the Week 17 start. The former Lions backup opened this season on the Vikings practice squad, but Arizona plucked him for its active roster on Dec. 14. The Cardinals now clearly believe him to be the better option than Trace McSorley. Blough won't be a meaningful fantasy option, and he's likely a downgrade vs. McCoy for Arizona pass-catchers -- if only because he hasn't been with the team as long. Of course, we'll also see about the status of WR DeAndre Hopkins, who is now dealing with knee trouble.

Who would have guessed that any NFL wideout would be excited to see Colt McCoy enter the huddle? Cardinals WR DeAndre Hopkins should feel that way when McCoy returns to action for this Sunday's game against the Falcons. Hopkins has been targeted on 37.1% of McCoy's pass attempts this season, drawing 11+ in every one of the QB's appearances. The 1st 2 came with WR Marquise Brown out, but Hopkins got 11 looks and tallied 7 catches the past 2 times with Brown back in the lineup. (Brown saw 8 targets in each of those contests.) Hopkins, of course, didn't have a target issue last week with QB Trace McSorley, who threw 10 passes his way. But Hopkins caught just 1 of those. He has caught at least 7 balls in every game that has involved McCoy. Atlanta arrives as the 6th-best scoring matchup for WRs, which obviously helps Hopkins. You'll find him prominent in our Week 17 WR rankings.

Cardinals QB Colt McCoy has cleared the concussion protocol and is expected to start Sunday's game vs. the Falcons, ESPN's Adam Schefter reports. McCoy is no savior, of course. But he's a significant upgrade over QB Trace McSorley. McCoy's return is good news for RB James Conner and WRs DeAndre Hopkins and Marquise Brown.

The Cardinals ruled QB Colt McCoy (concussion) out for Sunday's game vs. the Bucs. That leaves Trace McSorley under center for Arizona. McSorley started for 3 seasons at Penn State but completed just 59% of his passes. He went in the 6th round of the 2019 NFL Draft and has gone 15-of-29 for 166 yards, 0 TDs and 3 INTs in 3 appearances for the Cardinals this season. There's nothing to suggest that McSorley is an NFL-calibre QB. Consider him a significant downgrade from McCoy.

Cardinals QB Colt McCoy suffered a concussion in the 3rd quarter of Sunday's game vs. the Broncos. He's been replaced by QB Trace McSorley. We'll track McCoy's progress through the protocol this coming week.

Cardinals QB Kyler Murray went down with a non-contact injury on the 3rd play from scrimmage in Monday night's game vs. the Patriots. Murray had to be carted off the field and is certainly done for the night. We'll update Murray's status when we know more. QB Colt McCoy has replaced Murray.

Update: Murray has a knee injury and is officially "questionable" to return, the team announced.

Update: Murray has been downgraded to out.

Cardinals HC Kliff Kingsbury said Tuesday that QB Kyler Murray has progressed "quite a bit" with his hamstring injury. Kingsbury did not say whether Murray will be back for Week 12, though, saying that he needs to be "full throttle" before getting back under center. We'll track Murray's status throughout the week. Kingsbury also said that QB Colt McCoy is "banged up" with elbow, hand and knee injuries.

Cardinals QB Kyler Murray (hamstring) is inactive for tonight’s matchup with the 49ers. Colt McCoy will make his 2nd straight start.

ESPN's Jeremy Fowler reports that Cardinals QB Kyler Murray (hamstring) might not return until after the team's Week 13 bye, "depending how the injury heals this week." It's already assumed Murray will miss tonight's game against the 49ers. This would mean he also misses next Sunday's clash with the Chargers. We'll watch to see what happens on that front this week. Colt McCoy remains the next man up.

FOX's Peter Schrager reports that QB Colt McCoy is expected to start Monday night against the 49ers. That would mean a 2nd straight missed game for QB Kyler Murray (hamstring). We're updating the Week 11 fantasy football rankings to reflect the QB change, though the QB switch shouldn't make a huge difference for the outlooks of Arizona pass-catchers.

Cardinals HC Kliff Kingsbury said Friday that QB Kyler Murray's injured hamstring has "come a long way," according to ESPN's Josh Weinfuss. But the coach also said Murray will still be a game-time decision for Monday night against the 49ers. That late kick will make Murray difficult to wait for in fantasy football lineups unless you have Jimmy Garoppolo or Colt McCoy as insurance. We'll watch for early signals on the expectation for Murray's involvement.

Update: Murray is officially listed as questionable after getting in 3 limited practices this week.