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The Bengals list RB Joe Mixon as questionable for Sunday’s game vs. the 49ers. He missed practice all week with an illness. Mixon was at least watching on the sidelines on Friday, and HC Zac Taylor said afterward that he expects Mixon to play. We’ll continue looking for updates on his status. 49ers-Bengals doesn’t kick off until 4:25 pm ET on Sunday. Samaje Perine would be Cincinnati's lead back if Mixon is out this week.

Bengals RB Joe Mixon (illness) missed his 2nd straight practice on Thursday. Players rarely miss games with non-COVID illnesses, so we're expecting Mixon to play vs. the 49ers on Sunday. But check back tomorrow for another update on his status.

Bengals RB Chris Evans (hamstring) is out for Sunday's game against the Jets. Joe Mixon and Samaje Perine will handle all of Cincinnati's backfield work.

11:30am EDT 10/17/21

Bengals RB Joe Mixon (ankle) is active for today’s game against the Lions. He was listed as questionable after getting in only 2 limited practices this week. But HC Zac Taylor said Friday morning that Mixon “should get a full workload” vs. Detroit. RB Samaje Perine (COVID) is out, which can’t hurt Mixon’s volume. Consider him a risk/reward RB1 today.

Bengals RB Joe Mixon (ankle) is expected to play vs. the Lions today, according to ESPN's Adam Schefter. Mixon got in just 2 limited practices this week and is listed as questionable. But HC Zac Taylor said Friday that Mixon is ready for a full workload. Consider him a risk/reward RB1 in Week 6 fantasy lineups.

Bengals RB Joe Mixon (ankle) is listed as questionable for this weekend’s game against the Lions after getting in limited practices on Wednesday and Friday. That’s not a great look, but HC Zac Taylor said Friday morning that Mixon “should get a full workload” this weekend. RB Samaje Perine remains on the COVID list as of Friday afternoon, leaving RBs Chris Evans and Trayveon Williams behind Mixon on the depth chart.

Bengals HC Zac Taylor said Friday that RB Joe Mixon (ankle) "should get a full workload" against the Lions on Sunday. Mixon was obviously limited by that ankle last week but came out of that game without suffering a setback. He averaged 20.8 carries and 2.3 targets over the first 4 games of the season and should be in line for similar volume on Sunday.

Bengals RB Joe Mixon (ankle) did not practice on Thursday. He either suffered a setback with that ankle or got the day off. Tomorrow's practice participation and final injury report will tell the story. With RB Samaje Perine still on the COVID list, rookie Chris Evans could be left as the lead back for Sunday's game vs. the Lions.

Bengals RB Joe Mixon (ankle) was a limited participant in Wednesday's practice. It's good to see him out there early in the week after he gutted through that ankle injury last Sunday. Mixon is on track to play vs. the Lions this weekend, but it'd be nice to see him get in a full practice by the end of the week.

The Bengals have placed RB Samaje Perine on the COVID list. His specific status isn't yet clear, but he at least looks very iffy for Week 6. Perine isn't much of a standalone fantasy option when Joe Mixon is healthy, but he did eat up 11 carries (for 59 yards) and catch 4 balls for 24 yards and a TD in Sunday's loss to the Packers. Perine played more than 3 times as many snaps as Mixon in that game and beat him in rushing attempts and targets. As long as Mixon avoids any setback with his sprained ankle, we'd assume more work for the starter in this Sunday's visit to Detroit. If Perine is out, then Chris Evans should see some involvment. We wouldn't expect him to be an option for fantasy football lineups, though.

According to Jeremy Rauch of FOX 19 in Cincinnati, Bengals beat writer Geoff Hobson said this morning that he thinks RB Joe Mixon will get "pretty darn close to his normal work load" today. We're all guessing at how many touches Mixon will get and how his sprained ankle will hold up to it. Whether to start him in fantasy ultimately comes down to a personal call on risk vs. reward, plus the other options.

11:30am EDT 10/10/21

Bengals RB Joe Mixon (ankle) is active for today’s game vs. the Packers. NFL Network’s Ian Rapoport confirmed this morning that Mixon won’t be at 100%. We’re not expecting him to get his usual workload, leaving him as a risky fantasy play.

Bengals RB Joe Mixon (ankle) is expected to play vs. the Packers today, according to NFL Network's Ian Rapoport. Rapoport confirms that Mixon "won't be 100%" but doesn't say whether he'll be on any type of snap or touch count. We're expecting Mixon to be limited to some extent and would try to avoid Cincinnati's backfield in Week 5 fantasy lineups.

NFL Network's Tom Pelissero reports that Bengals RB Joe Mixon (ankle) is trending toward playing "in some capacity" vs. the Packers tomorrow. His Saturday morning workout evidently went well. Of course, the report makes it sound like Mixon will be limited to some extent. The exact extent is unclear, leaving fantasy owners in a tough spot. We'll look for further updates on the situation, but Mixon is still better off on fantasy benches right now. Same goes for RB Samaje Perine unless Mixon ends up inactive tomorrow.

The Bengals list RB Joe Mixon (ankle) as questionable for Sunday's game vs. the Packers. He didn't practice all week, but HC Zac Taylor said they'll test that ankle on Saturday. We'll look for further updates and will get Mixon's game status by noon ET on Sunday. He'll obviously carry elevated risk if he ends up active. If not, look for RB Samaje Perine to lead a committee attack ahead of RB Chris Evans.

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