Giants RB Saquon Barkley (ankle) missed practice again on Friday. He's not going to play vs. the Chiefs of Monday night, giving RB Devontae Booker another start.

Giants HC Brian Daboll labeled RB Saquon Barkley "day-to-day" with his ankle injury. "He feels a lot better today, but we’ll kinda take that all the way throughout the week and see how he improves,” Daboll said. Barkley has an extra day to get ready for New York's Monday night game vs. the Seahawks, but we'd still consider him no better than 50/50 for that one after Barkley revealed last week that he's dealing with a high-ankle sprain.

Giants RB Saquon Barkley (ankle) "has a chance" to play vs. the Seahawks next Monday night, according to NFL Network's Ian Rapoport. That'd be a quick return from a high-ankle sprain, but we'll keep a close eye on Barkley's progress this coming week.

Giants RB Saquon Barkley told NFL Network's Taylor Rooks that he's dealing with a high-ankle sprain. Previous reports had it as a low-ankle sprain. Those tend to be less significant than high sprains. Barkley also told Rooks that his injury isn't as severe as it could have been but that he's not sure if he'll be ready for Week 4. High-ankle sprains usually cost guys at least 3-4 weeks, so Barkley owners should prepare to be without him beyond Week 3. We'll continue to track his rehab.

The Giants have officially ruled RB Saquon Barkley out for Thursday night's game against the 49ers. That's been expected since news broke of his Week 2 ankle sprain. Matt Breida is expected to be the first guy up in the Week 3 backfield, but that's only enough to land him in RB4 territory in our Week 3 RB rankings. Expect Gary Brightwell and rookie Eric Gray to mix in as well for a backfield that has been limited even with Barkley through two weeks.

Giants RB Saquon Barkley (ankle) did not practice on Tuesday. HC Brian Daboll said earlier in the day that Barkley still has a chance to play vs. the 49ers on Thursday night, but we're not buying it. We'll see how he's listed on the final injury report tomorrow.