Rams RBs Cam Akers and Darrell Henderson are "good to go," HC Sean McVay said Friday. Both backs missed time in August with soft-tissue injuries but got back on the practice field earlier this week. They're both on track to play in Thursday night's season opener vs. the Bills. Then we'll start to get an idea of what the backfield split will look like.

Vikings HC Kevin O'Connell said RB Cam Akers "more than likely" won't play vs. the Chargers on Sunday. O'Connell does expect Akers to be ready for Week 4. But RB Alexander Mattison will get at least one more game as Minnesota's feature back.

On Wednesday, ESPN's Adam Schefter reported that the Rams are trading RB Cam Akers to the Vikings in exchange for a swap of 2026 NFL Draft picks. Akers was a surprise inactive on Sunday vs. the 49ers, and HC Sean McVay reiterated to the media on Monday that the team was trying to deal away the former second-round pick. This news brings the "will they, won't they" saga dating back to the 2022 season to a close and also muddies the outlook for incumbent Vikings RB Alexander Mattison. Fantasy managers who roster Mattison will now have to worry about Akers, who has connections to HC Kevin O'Connell and OC Wes Phillips dating back to their days in Los Angeles, coming in and taking away some work. This could be merely a depth move, though Mattison has not been particularly effective this season, averaging just 31.0 rushing yards per game. Stay tuned for more updates regarding the fantasy fallout of this trade.

On Monday, ESPN's Sarah Barshop tweeted that Rams HC Sean McVay told reporters that GM Les Snead has spoken with "a handful of teams" regarding a trade for RB Cam Akers and "that's the direction" the Rams are headed. This would seem to indicate that RB Kyren Williams will remain the most fantasy-relevant back in Los Angeles for the time being. Even so, there's nothing stopping the Rams from adding another back to the depth chart at some point down the line. We'll keep an eye on how this situation continues unfolding in the coming days.

Rams RB Cam Akers is a healthy scratch for today's game vs. the 49ers, as Fox Sports' Jay Glazer reported would be the case a few minutes before 1 pm ET this afternoon. RBs Kyren Williams, Ronnie Rivers, and Royce Freeman are active for Los Angeles. Williams figures to handle the majority of the backfield work.

Rams RB Cam Akers will be a healthy scratch for this afternoon's game vs. the 49ers, according to Fox Sports' Jay Glazer. Glazer adds that some teams believe Akers is on the trade block. Hopefully you weren't counting on him in Week 2 fantasy lineups. The news makes RB Kyren Williams easier to trust in fantasy lineups, despite the negative matchup.