Bills RB Damien Harris has a neck sprain "but is otherwise good," a source tells insider Jordan Schultz. It's excellent news after Harris was taken off the field in an ambulance during Sunday night's game vs. the Giants. We'll look for further updates on when Harris might be able to get back on the field. His absence figures to boost RB Latavius Murray's workload.

Bills QB Josh Allen injured his right shoulder in the second quarter of Sunday night's win over the Giants. He wound up missing just one play. Allen said afterward that the shoulder issue didn't impact his throwing and that scans came back "normal." He's scheduled for additional testing on Monday, according to NFL Network's Ian Rapoport. We'll keep a close eye on this one, but it seems like Allen will be available for this weekend's game vs. the Patriots.

Bills WR Stefon Diggs delivered a star performance in Week 6, logging 10 catches on 16 targets for 100 receiving yards vs. the Giants. Beyond him, no other Bills’ pass-catcher exceeded 3 catches or 25 receiving yards in the contest. Sunday night saw an uncharacteristically lousy performance from Buffalo, though their collective efforts were enough to pull out the victory. Next week’s divisional showdown vs. the struggling Patriots should present solid grounds for more Bills besides Diggs to deliver fantasy production.

Bills RB James Cook received 14 carries for 71 yards in Week 6's win vs. the Giants. Surprisingly, the second-year back didn't register a single target or catch in the contest, the first time that's happened in the 2023 season. After Damien Harris left late in the second quarter due to a frightening neck injury, RB Latavius Murray stepped up in spelling Cook and ended Sunday night with 45 rushing yards on 12 carries. It's also worth noting that Murray received 4 red zone carries to Cook's 1 against the Giants. Though the veteran didn't find the end zone, Murray brings some fantasy viability as a decent flex option with TD upside for managers with players on bye weeks. Next week, the Bills will take on the Patriots.

Bills QB Josh Allen completed 19 of 30 attempts for 169 yards with 2 TDs and 1 INT in Sunday night’s narrow victory vs. the Giants. Week 6 was not the strongest showing from the Bills offense as a whole, and the team struggled throughout the contest. It wasn’t until the third quarter that Allen and company successfully executed a score or gained more than 40 yards on a single drive. Week 7 presents a solid opportunity for Allen to get back to his dominant ways against a struggling Patriots defense.

Bills RB Damien Harris was put on a stretcher and taken off the field in an ambulance in the second quarter of Sunday night's game vs. the Giants. He gave a thumbs up prior to loading into the ambulance. We'll update his status when we know more.

Update: Harris has a neck injury but has movement in his arms and legs, per the NBC broadcast. Harris is headed to the hospital for further testing.

Bills TE Dawson Knox (wrist) is active for tonight's game vs. the Giants. TE Dalton Kincaid (concussion) is inactive. That should mean a boost in pass routes for Knox, making him a passable season-long starter and an intriguing play in one-game DFS contests.

Bills TE Dawson Knox (wrist) is expected to play vs. the Giants tonight, ESPN's Adam Schefter reports. No word on TE Dalton Kincaid, who's listed as questionable with a concussion. Kincaid should not be in Week 6 fantasy lineups at this point. And Knox is only worth considering if we hear that Kincaid will not play tonight.

The Bills left Edge Greg Rousseau off the final Week 6 injury report. That means the foot issue that cost him last week's game against the Jaguars shouldn't get in the way for this week's high-upside matchup with the Giants. Rousseau put in a pair of limited practices before going full Friday. He's attractive for IDP lineups this week.

Bills TE Dawson Knox (wrist) is listed as questionable for Sunday night's game vs. the Giants. He was limited in practice all week. We'll look for an update on his status on Sunday morning. If Knox plays -- and TE Dalton Kincaid (concussion) is out -- Knox would be in the TE1 discussion with Buffalo sporting a big 29.75-point implied total.

Bills TE Dalton Kincaid (concussion) is listed as questionable for Sunday night's game vs. the Giants. He remained limited in practice all week, so he still has multiple stages of the concussion protocol to clear. We're not expecting Kincaid to play on Sunday but will continue to track his progress.

Bills TEs Dalton Kincaid (concussion) and Dawson Knox (wrist) got in limited practices on Wednesday. That gives both guys a shot to play vs. the Giants on Sunday night. We'll track their progress over the next few days.

Bills TE Dawson Knox came away from Week 5 with a wrist injury, HC Sean McDermott told reporters Monday. He said they'll see how Knox fares in practice this week. Buffalo could be down to its third TE for Week 6, as Dalton Kincaid's dealing with a concussion. We'll track both players through the practice week.

Bills HC Sean McDermott revealed Monday that TE Dalton Kincaid is in the concussion protocol. That bodes ill for his chances of playing Sunday against the Giants. We'll see about the team's plan at TE, where Dawson Knox is also dealing with an injury. Missing both would leave more targets available for the WRs and RB James Cook.

Bills LB Matt Milano suffered a leg fracture and is feared to have also suffered a season-ending knee injury, according to NFL Network's Ian Rapoport. Milano left Sunday morning's loss to the Jaguars early after hurting his right leg, and it sounds like he could be in for a rough recovery. We'll watch for more on his return timeline, but you should expect to lose Milano from your IDP roster for the rest of the season.

Bills WR Stefon Diggs posted a team-leading 121 receiving yards with 8 catches on 11 targets and 1 TD in Week 5 vs. the Jaguars. Teammate Gabriel Davis also posted a 100-yard game to go along with 6 catches and a TD in the contest. Though neither player produced much in the box score, it’s worth mentioning that TE Dawson Knox out-targeted rookie Dalton Kincaid 6 to 2 on Sunday. The pair is now tied with 19 targets apiece this year, but the split in work makes it difficult to trust either moving forward. We’ll get another look at the Bills in Week 6 vs. the Giants.

Bills RB James Cook hauled 3 of 4 targets for 25 receiving yards in Week 5’s loss vs. the Jaguars. He was unfortunately not as effective as a runner, totaling -4 yards on 5 carries. His teammate Damien Harris didn't do much better, leading all Bills RBs with 13 yards on 3 carries. The Jaguars’ defense entered Week 5 as the sixth-toughest matchup in adjusted fantasy points allowed to RBs in 2023 and did a tremendous job of stopping runners again this week. We expect Cook and company to have a much better time in Week 6 vs. the Giants.

Bills QB Josh Allen completed 27 of 40 attempts for 359 passing yards with 2 TDs and 1 INT in Week 5’s loss vs. the Jaguars. He also added 14 yards and a TD as a rusher in the contest. Allen helped to orchestrate a comeback late in the game with back-to-back 75-yard scoring drives, though the Bills came up just shy of the victory in London. Still, fantasy managers are happy with the production Allen provided. He’ll be a high-end QB1 again next week against the Giants in Week 6.

Bills LB Matt Milano left with a knee injury in the first half against the Jaguars. The team quickly ruled him out for the game. That doesn't bode well for Milano's outlook, and it's not shocking given how much help Milano needed getting off the field. We'll watch for more on his return timeline.

Bills S Jordan Poyer (knee) is off the final injury report ahead of Sunday's game against the Jaguars. That means he's ready to return after missing last week's game. CB Christian Benford (shoulder) is questionable after leaving Week 4 early. He was limited in practice all week.