Bills RB Zack Moss is a healthy scratch for tonight's game vs. the Saints. Buffalo will roll with RBs Devin Singletary and Matt Breida. "I think it'll be a 1A/1B situation unless someone gets hot," The Athletic's Joe Buscaglia wrote, labeling Singletary the 1A. In a matchup vs. the league's top-ranked RB defense, consider Singletary and Breida just RB3 or flex options.

Bills LB Tremaine Edmunds (hamstring) is inactive for today's game against the Colts. That leaves A.J. Klein in position for full playing time, a role in which he delivered nice fantasy numbers last week.

Dolphins RB Duke Johnson has been promoted to the active roster. He'll presumably be active for tomorrow's game vs. the Jets, alongside RBs Myles Gaskin and Salvon Ahmed. We wouldn't expect Johnson to steal more than a few touches from Gaskin.

Bills LB Tremaine Edmunds (hamstring) is questionable for Sunday's game against the Colts. He missed practice Wednesday and Thursday after sitting out last week's win over the Jets. Edmunds returned for a limited Friday workout, though. We'll check his status Sunday. IDP managers might be better off if he doesn't play, as an active Edmunds would carry elevated re-injury risk. If he's out, A.J. Klein would see a full-time role again.

Rams EDGE Von Miller (ankle) is active for tonight's game against the 49ers. Miller entered the day questionable, but ESPN's Adam Schefter previously reported that the team wouldn't play Miller until he was close to "fully healed." Play Miller if you waited on him for your IDP lineup. A near-healthy Miller should enhance the L.A. defense. CB Darious Williams (ankle) is also active after entering the night questionable.

Bills RB Zack Moss (concussion) is active for today’s game vs. the Jets. He figures to continue splitting backfield work with Devin Singletary, leaving both guys as just RB3 or flex plays.

Rams OLB Von Miller is officially questionable for Monday night's game against the 49ers. ESPN's Adam Schefter reports that they won't play Miller "unless the team believes his ankle injury is close to fully healed." He adds that the injury was worse than the Rams realized when they made the trade. A Week 11 bye could factor into the decision on whether to play him. At the least, the Monday night kickoff makes it difficult to wait on Miller for IDP rosters. Rams CB Darious Williams is also questionable after popping up on the injury report Friday with an ankle issue that kept him out of Saturday's practice. He's not worth waiting on.

Bills RB Zack Moss has cleared the concussion protocol, according to NFL Network's Ian Rapoport. Barring a setback, Moss will be available for Sunday's game vs. the Jets. He had been operating as Buffalo's lead back but was out-carried 5 to 3 by Devin Singletary before exiting last week's loss to Jacksonville. Moss and Singletary both look like RB3s with upside vs. the Jets tomorrow.

Bills RB Zack Moss (concussion) is listed as questionable for this weekend’s game vs. the Jets. He got in limited practices on Thursday and Friday. The Athletic’s Joe Buscaglia notes that Moss was not wearing a non-contact jersey on Friday, so he seems to be making good progress through the protocol. We’ll see whether he can get full clearance in time for Sunday’s game. If not, Devin Singletary would be Buffalo’s clear lead back -- and a RB2 in fantasy lineups.

Bills TE Dawson Knox (hand) is not listed on the final injury report. He practiced all week, including full workouts on Thursday and Friday. We’re not expecting Knox to be limited in Sunday’s game vs. the Jets. He was sitting 4th among TEs in half-PPR points through Week 6.

Bills HC Sean McDermott said on 550 WGR Friday that MLB Tremaine Edmunds will miss Sunday's game against the Jets with a hamstring injury. Expect Tyrel Dodson to start in his place. CB Taron Johnson (concussion) is expected to play, though, after coming out of the league protocol Friday.

Bills RB Zack Moss (concussion) returned to a limited practice on Thursday. He's made some progress through the protocol, giving him a shot to be cleared in time for Sunday's game vs. the Jets. We'll get another update on his progress tomorrow.

Bills TE Dawson Knox (hand) was upgraded to full participation in Thursday's practice. He's on track to return for this weekend's game vs. the Jets. Knox averaged 4.5 targets, 3.5 catches, 47.7 yards and .8 TDs over the first 6 weeks of the season.

Bills RB Zack Moss (concussion) did not practice on Wednesday. He's looking unlikely to play vs. the Jets this weekend. Moss' absence would put Devin Singletary in the RB2 mix.

Bills TE Dawson Knox (hand) returned to a limited practice on Wednesday. Week 10 has been the target for his return from that broken hand, and he appears to have a good chance to play vs. the Jets on Sunday. Check back tomorrow for another update.

Bills MLB Tremaine Edmunds came away from Sunday's loss to the Jaguars with a hamstring injury. ESPN's Alaina Getzenberg reports that Edmunds will miss Wednesday's practice. We'll see whether he progresses through the week.

Bills CB Taron Johnson left Sunday's loss to the Jaguars with a concussion. He'll need to pass through the league protocol before returning. Siran Neal will fill in if Johnson misses further time.

New Rams OLB Von Miller will miss his 1st game with the new team. He's inactive with the ankle injury that also cost him his final game in Denver. LB Ernest Jones (illness) and CB Jalen Ramsey (knee) are active, however, after hitting the day questionable.

Bills RB Zack Moss sustained a concussion in the 2nd half of Sunday's game vs. the Jaguars. It's his 1st documented concussion. We'll track his progress through the protocol this coming week.

Bills S Jordan Poyer (shoulder) is active for today's game against the Jaguars.