Fantasy Football News

49ers RB Christian McCaffrey (calf) will not play vs. the Rams this weekend, HC Kyle Shanahan confirmed Monday. Shanahan called McCaffrey's injury a "mild calf strain." It's unclear if CMC would be able to play if this game meant something to San Francisco, but he was never going to suit up with the NFC's No. 1 seed clinched. He'll get three total weeks to heal up before the 49ers' playoff opener. We'll see about the team's backfield plans this weekend. RBs Elijah Mitchell and Jordan Mason are on the active roster, with RB Ty Davis-Price on the practice squad.

49ers RB Jordan Mason “appears” to be the favorite for the RB3 role, per beat writer Jack Hammer. Mason's main competition is 2022 Round 3 pick Tyrion Davis-Price. “The second-year back is a more fluid runner and does a better job of setting up his blockers than Ty Davis-Price,” Hammer writes. “He has also looked much better in pass protection, squaring up defenders consistently.” We’ll see what the rest of the preseason brings. But the RB3 role in San Francisco figures to have some fantasy relevance this season — especially with No. 2 Elijah Mitchell already battling an adductor injury.

49ers RB Christian McCaffrey (knee) is not listed on the final injury report. He went from no practice on Wednesday to limited Thursday to full participation on Friday. McCaffrey is believed to be dealing with knee tendinitis, but we’re not expecting it to significantly impact him in Sunday’s game vs. the Dolphins. RB Elijah Mitchell is expected to miss the rest of the regular season with his MCL sprain, leaving some combination of Ty Davis-Price, Jordan Mason and Tevin Coleman behind McCaffrey.

49ers RB Ty Davis-Price (ankle) is not listed on the final injury report and will be available for Sunday’s game vs. the Falcons. Assuming the rookie is active, he figures to be 3rd on the depth chart behind RBs Jeff Wilson and Tevin Coleman.

49ers RB Ty Davis-Price suffered a high-ankle sprain in Sunday's win over the Seahawks, HC Kyle Shanahan said. That injury typically costs guys 4-6 weeks. Davis-Price handled 14 carries behind RB Jeff Wilson's 18 in Week 2. San Francisco is now down to RBs Jordan Mason and Marlon Mack behind Wilson. Mason has been active the first 2 weeks but has yet to play an offensive snap. Mack couldn't make Houston's final roster. Wilson has a good chance to control backfield work until RB Elijah Mitchell returns from his knee injury.

ESPN's Adam Schefter reports 49ers QB Trey Lance suffered a "significant" right ankle injury in the Week 2 win over the Seahawks. Lance is expected to need surgery that will "likely" end his season. You can hang on to him on fantasy rosters until we get official confirmation that Lance's season is over, which figures to come tomorrow. San Francisco will turn back to QB Jimmy Garoppolo, which will mean a significant shift in the offense. The 49ers' pass rate will climb, and there will be more carries to go around since Garoppolo won't be taking many.

49ers RB Elijah Mitchell is expected to miss "a few weeks (or more)" with the knee injury he suffered in Sunday's opener vs. the Bears, per NFL Network's Ian Rapoport. Mitchell is undergoing an MRI on Monday to get a full view of the damage to the knee. We should get a more concrete timeline for his return over the next couple days, but fantasy owners need to start making replacement plans. Jeff Wilson is the favorite to take over as San Francisco's lead RB, but Jordan Mason and Ty Davis-Price are also worth stashing.

The 49ers lost RB Elijah Mitchell (knee) early in Sunday's loss to the Bears, which left Jeff Wilson Jr. as the clear backfield leader. With rookie RB Tyrion Davis-Price a healthy scratch, Wilson led RBs at 59% playing time and claimed 9 of 15 RB carries. He managed just 22 yards on the ground, adding 8 more on 2 receptions (2 targets). Deebo Samuel served as the other primary -- and only productive -- runner vs. Chicago, including scoring the team's only TD. RB Jordan Mason was active but didn't get onto the field. We'll see about the outlook for Mitchell's injury and who joins Wilson in the backfield. But he looks like the best bet to lead 49ers RBs in opportunities while Mitchell is out.

NBC Bay Area's Matt Maiocco says 49ers HC Kyle Shanahan "appears determined to deploy more of a backs-by-committee approach" this season. That would obviously hurt the touch count for RB Elijah Mitchell, who averaged 18.8 carries per game as a rookie. He also missed 6 games with multiple injuries, though, and needed a knee "clean-up" after the season. San Francisco added RB Tyrion Davis-Price in Round 3 of the NFL Draft and get Jeff Wilson Jr. back to full health after he basically lost 2020 to a meniscus tear. Trey Sermon and JaMycal Hasty also remain but will likely need to fight their way into contention for touches. Mitchell is going RB24 in FFPC drafting and RB23 on Underdog right now. That's not a terrible range, but we're not excited about his 2022 outlook -- especially in full-PPR formats.

Jeff Wilson will head to training camp as the 49ers' #2 RB, according to The Athletic's Matt Barrows. Wilson "looked significantly better in the spring than he did late last season when he was still dealing with the aftereffects of an offseason knee injury," Barrows writes. RB Ty Davis-Price, meanwhile, missed some time this spring with an injury. There's still plenty of time for the rookie to climb the depth chart, but don't assume that TDP will begin the season as RB Elijah Mitchell's backup.