RB Alexander Mattison sits second on the Vikings' depth chart right now. But he'll climb a peg if RB Dalvin Cook is traded or released. And HC Kevin O'Connell sounds confident that Mattison could handle the lead role. “It’s been really good to see Alex Mattison take a few more reps and really show that all three-down kinda ownership that he’s been capable of for a long time,” O’Connell said Wednesday. Mattison has shown the ability to handle hefty workloads in the past. He's topped 20 touches five times over the last three seasons. His RB29 ADP in recent FFPC drafts will prove to be a bargain if Cook departs before Week 1.

The Vikings will go with the hot hand at RB vs. the Panthers today, according to NFL Network's Tom Pelissero. RB Alexander Mattison "is still the starter," per Pelissero, but we could see "a lot of" RB Cam Akers. Mattison has been inefficient and mistake-prone through three games, so there's an opening for Akers. Mattison remains the preferred fantasy play today, but his floor is much lower than it's been the first three weeks.

The Vikings made RB Cam Akers inactive for his first game with the team. So RB Alexander Mattison continued to dominate backfield usage. He took 20 carries for 93 yards and added a 5-32 receiving line on 7 targets. Mattison benefited from facing a weak Chargers D and from Minnesota running 83 offensive plays. But we'll have to assume he retains the clear backfield lead until/unless something changes. Week 4 holds a high-upside matchup with a Panthers D that has been run over so far this season.

Vikings RB Alexander Mattison mustered just 28 scoreless yards on eight carries (3.5 YPC) in Thursday night’s loss to the Eagles. He turned six targets into three catches and 11 yards. Mattison has now totaled 83 yards on 25 touches through two games this season — an ugly 3.3 yards per touch. He hasn’t gotten much help from his offensive line but also hasn’t made much happen on his own. Mattison continued to dominate the backfield work vs. Philadelphia, with RB Ty Chandler getting just one carry and two targets. But we could see Chandler’s role grow if Mattison doesn’t start producing more. Mattison's RB2 status is on very shaky ground.

Vikings RB Alexander Mattison out-carried Ty Chandler 11-3 in Sunday’s loss to Tampa Bay. Mattison didn’t find much room to run, but he salvaged his day with an excellent individual effort on a goal-line receiving TD. Mattison also ran 22 routes to only 7 for Chandler, so there’s no concern over the passing-game role. Week 2 brings a tough matchup with Philly, but Mattison will remain an RB2. Keep Chandler stashed as a high-value handcuff.

"Do not underestimate the Vikings’ commitment to [RB Alexander] Mattison," The Athletic's Alec Lewis writes. "The team believes in him and it believes he is a key cog in their attempt at improved rushing efficiency. Mattison might not provide the explosive element that [RB Dalvin] Cook possesses, but the Vikings are committed to providing him an every-down workload." Mattison isn't the most exciting talent, but everything we've heard from Minnesota since Cook's departure is that Mattison is in for big volume this year. He's a solid pick in the fifth or sixth round of fantasy drafts.