49ers TE George Kittle (ankle) did not practice on Wednesday. “He’s got a chance, so we’re not ruling him out," HC Kyle Shanahan said. We'll hopefully have a good idea of Kittle's status for the Bears game by Sunday morning, but we won't get San Francisco's inactives until a little before 7 pm ET. Fantasy managers hoping to start Kittle should stash TE Jake Tonges as insurance.

49ers TE George Kittle suffered a “mid-to-low ankle sprain" in Monday night's win over the Colts, according to ESPN's Jeremy Fowler. That's better news than a high-ankle sprain but still leaves Kittle uncertain for Sunday night's game against the Bears. We'll keep tabs on his status throughout the rest of the week. Kittle's absence would turn TE Jake Tonges into an intriguing spot starter. He averaged 6.2 targets, 4.4 catches, 41.8 yards, and 0.4 TDs in the five games Kittle missed early this season.

49ers TE George Kittle hurt his left ankle in the third quarter of Monday night's game vs. the Colts. He was visibly frustrated as he made his way off the field. Kittle was deemed questionable to return and remained on the sidelines, but he never made it back onto the field. He had a monster game before exiting, catching 7 of 8 targets for 115 yards and a score. But his availability for Sunday night's game vs. the Bears is now uncertain. HC Kyle Shanahan didn't have an update on the injury afterward. We'll keep you posted.

49ers WR Ricky Pearsall (ankle, knee) is out for Monday night's game vs. the Colts. He didn't practice all week and could certainly miss multiple games after aggravating his PCL injury last week. Pearsall's absence boosts the target projections on WR Jauan Jennings and TE George Kittle.

The forecast for today's 49ers-Browns game calls for sustained winds of 25 mph with gusts around 35 mph. The total in this game has dropped from 42.5 to 35.5. Expect a run-heavy game plan from both sides. RBs Christian McCaffrey and Quinshon Judkins can stay in fantasy lineups. TE George Kittle is the only comfortable play from either passing game. Avoid the kickers.

Niners TE George Kittle officially returned from his hamstring injury in Week 7. But he wound up just short of his usual playing-time share, drew just two targets, and produced nary a catch. Kittle re-emerged in Sunday's loss to the Texans, tying for the team lead with 4 receptions. Kittle tallied 43 yards and caught one of Mac Jones' 2 TD passes. The other scoring toss frustratingly went to TE Jake Tonges on a fourth-quarter route that ran him right in front of Kittle.

49ers TE George Kittle (hamstring) is off the final Week 7 injury report. He practiced all week, including a full workout on Friday. HC Kyle Shanahan said Friday that Kittle won’t have any limitations against the Falcons on Sunday night. "No pitch count," Shanahan said. "George has rehabbed really well. He came back 100% and had a good week of practice, so we’ll space it out throughout the game but no pitch count." There’s still some risk of re-injury here, but Kittle is back near the top of the Week 7 TE rankings.

49ers TE George Kittle (hamstring) remained limited in practice on Wednesday, but he said afterward that he "fully plans" on playing vs. the Falcons on Sunday night, according to ESPN's Nick Wagoner. Kittle added that the final decision rests with HC Kyle Shanahan but that he expects to get the green light. We'll see how Kittle is listed on Friday's final injury report and look for further updates on the 49ers' plans for Kittle in his first action since Week 1.

49ers TE George Kittle (hamstring) was officially limited in Wednesday's practice. The Athletic's Matt Barrows writes that Kittle had "HIGH ENERGY" in the portion of practice open to media. We're expecting Kittle to return for Sunday night's game vs. the Falcons, but we'll continue to keep an eye on his status over the next few days.

49ers HC Kyle Shanahan said Friday that TE George Kittle (hamstring) is a "long shot" to have his practice window opened next week. The following week is more likely, Shanahan said. We can safely assume Kittle will not play in Week 6, and we'd consider him 50/50 for Week 7 considering he'll need some time to ramp back up coming off the extended layoff. TE Jake Tonges has averaged 6.0 targets, 4.0 catches, and 37.8 yards with Kittle out over the last four weeks.

49ers TE George Kittle (hamstring) is "doing great" and has a "real chance" to return for Week 6, according to NFL Network's Ian Rapoport. That's when Kittle is first eligible to come off IR. He'll carry elevated risk of re-injury in his first game or two back. But Kittle will immediately slot back into the top 5 in our TE rankings as soon as he's active. We'll keep you updated on his status next week.

The 49ers placed TE George Kittle on Injured Reserve. Kittle will miss a minimum of 4 games.

Several reports have 49ers TE George Kittle missing multiple weeks with the hamstring injury he suffered in Sunday's win over the Seahawks. NFL Network's Ian Rapoport reports it'll likely be 3-5 weeks. His absence means more playing time for TEs Luke Farrell and Jake Tonges, but neither makes for an attractive addition in fantasy leagues right now. We'll see whether Kittle lands on IR, which would tell us more about his return timeline.

49ers TE George Kittle suffered a hamstring injury in Sunday's opener vs. the Seahawks and has been ruled out. Kittle missed two games last year with separate hamstring injuries and also dealt with hamstring trouble in training camp in 2017 and 2020. We'll see how much time Kittle will miss with his latest issue. His absence leaves Luke Farrell as San Francisco's lead TE, but he's not worth adding to fantasy rosters.

The San Francisco 49ers have placed WR Brandon Aiyuk on the PUP list, according to Adam Schefter of ESPN. He’ll miss at least the four weeks of the season.

Niners HC Kyle Shanahan told reporters Monday that all the team's "ACL guys" -- in the words of The Athletic's Matt Barrows -- are on track to return around Week 6. That includes WR Brandon Aiyuk, of course.