The Panthers have activated RB Christian McCaffrey (hamstring) from IR. Both Ian Rapoport and Mike Garafolo of NFL Network report that the team "hopes" McCaffrey will play Sunday against the Patriots. Make sure to check his game status Sunday morning if you're planning to play McCaffrey in your fantasy football lineup.

The Panthers have placed Christian McCaffrey on IR for the 2nd time this season, following his left-ankle injury in Sunday's loss to the Dolphins. That automatically knocks him out for the rest of the year, since it's his 2nd IR stint. It's a surprising development after NFL Network's Ian Rapoport reported earlier Monday that the injury "doesn't seem major." We'll see about the specifics of the injury, but that won't really matter until we're evaluating McCaffrey for 2022 fantasy football drafts. For now, it's Chuba Hubbard back to the lead at the position in Carolina. He averaged 17.8 carries, 65.8 yards and 0.4 TDs per game rushing in 5 fill-in starts earlier this season, with another 2.6 receptions and 17.6 receiving yards per contest. The Panthers have since added RB Ameer Abdullah, who figures to steal some passing-down snaps from Hubbard the rest of the way. Abdullah has seen 4+ targets in 4 of the past 5 games, averaging 2.6 catches and 22.4 receiving yards per game over those 5 contests.

Panthers RB Christian McCaffrey's ankle injury "doesn't seem major," NFL Network's Ian Rapoport says. That's the vibe we've gotten since CMC exited in the 1st half of Sunday's blowout loss to the Dolphins. McCaffrey is scheduled for additional testing, so we should get another update on his status later today. He gets a well-timed Week 13 bye and seemingly has a chance to be ready for Week 14.

Panthers RB Christian McCaffrey rolled his left ankle near the end of the 1st half of Sunday's game vs. Miami. The team never officially announced an injury, but McCaffrey didn’t record a touch in the 2nd half. HC Matt Rhule said afterward that McCaffrey tried to re-enter but couldn’t get comfortable on the ankle. He now gets a Week 13 bye to heal up.

Panthers RB Christian McCaffrey "rolled his ankle" near the end of the 1st half of Sunday's game vs. Miami, according to Fox's Jen Hale. There's been no official announcement from the team yet, but CMC wasn't on the field to start the 2nd half. Stay tuned.

Panthers RB Christian McCaffrey (hamstring) is active for today’s game against the Patriots. It’ll be his first action since Week 3. HC Matt Rhule said earlier this week that it won’t “be a 40- to 50-play situation” for McCaffrey, so don’t expect the usual 20+ touches. But CMC is still probably a starter for most fantasy teams. See where he sits in the Week 9 RB Rankings.