Colts beat writer Jake Arthur calls interior O-line depth one of the team’s biggest holes. Looking across the O-line, Indy’s lost 2,242 snaps with the offseason departures of LT Eric Fisher and OGs Mark Glowinski and Chris Reed. We’re not concerned for Matt Ryan or Jonathan Taylor, as the Colts return an excellent trio of OG Quenton Nelson, C Ryan Kelly and RT Braden Smith. This O-line is simply a unit to monitor going forward.

Colts QB Matt Ryan followed a shaky 1st outing with an even worse Week 2. He took 5 sacks and tossed 3 INTs in Sunday's 24-0 defeat at the hands of Jacksonville. Ryan completed just 16 of his 30 passes for only 195 yards. He was missing lead WR Michael Pittman and WR Alec Pierce against Jacksonville, which didn't help. WR Ashton Dulin led the team in targets (7), receptions (5) and receiving yards (79). Dezmon Patmon (6) and Nyheim Hines (5) were the only others to see more than 3 targets. Parris Campbell, meanwhile, drew just 2 looks and finished without a catch. He also doesn't need to remain on fantasy football rosters.

QB Matt Ryan racked up 352 yards in his Colts debut. He did so primarily thanks to 50 pass attempts, though (7.0 yards per attempt), completing 32 for 352 yards, with 1 TD and 1 INT (by EDGE Jerry Hughes on an attempted screen pass). It was not a great debut for Ryan, though fantasy drafters didn't hit the season expecting big things.

Colts HC Frank Reich said QB Matt Ryan will play the 1st quarter of Saturday's preseason opener against the Bills.

Colts HC Frank Reich discussed the offense’s up-tempo style at training camp. “It’s unbelievable,” Reich said of new QB Matt Ryan pushing the pace. “We’ve never practiced like this. It’s a mentality, a confidence. It’s ‘we got to keep up and play.’ We are dictating tempo from the huddle to the ball and we are going. (Ryan) told me at the start, ‘I’m going to push the tempo. I said, ‘We will follow your lead.’” Indy ranked 21st in plays per game last year, so perhaps we see a bump up in 2022. While we’re not targeting Ryan in fantasy drafts, we do like his presence for 3rd-year WR Michael Pittman.

Colts QB Matt Ryan impressed coaches, teammates and the media with his play and leadership this offseason. “Matt was unbelievable,” HC Frank Reich said. “Really, A-Z, he did everything right. Just great leadership, great play. I mean, the whole way he took command … I knew he was good, but his accuracy is insane." OC Marcus Brady said Ryan is "damn near a coach on the field." And rookie WR Alec Pierce said, "He could basically run this offense and this team by himself." We'd expect the 14-year veteran to impress in the intangibles department. But, by all accounts, Ryan's arm strength and accuracy were excellent over the past few months. He's still not an exciting fantasy asset in a run-first offense and without rushing upside. But Ryan's arrival could be a boost for the Colts' skill-position players.