Eric Branch of the San Francisco Chronicle writes: "The first three completions in Tuesday’s practice went to the same player: Brandon Aiyuk. In other words, the still-sizzling wide receiver finished camp the way he started, and he appears poised for a breakout third NFL season.” The buzz has followed Aiyuk for weeks and pushed his ADP up some. He still resides well into WR3 territory in most cases, though, a level that allows for plenty of upside room. Aiyuk's potential ascension could lower the ceiling for WR Deebo Samuel by siphoning target share in what we expect to be 1 of the league's most run-leaning offenses. We've been much more interested in Aiyuk than Samuel at their relative draft costs.

49ers WR Brandon Aiyuk (shoulder) is not listed on the final Week 4 injury report. He put in a full practice on Friday and seems ready to play his usual role vs. the Cardinals this weekend. With WR Deebo Samuel banged up, Aiyuk should be in for plenty of volume.

49ers WR Brandon Aiyuk (shoulder) remained limited in Thursday's practice but was out of his non-contact jersey, according to The Athletic's David Lombardi. Aiyuk is trending toward returning for this weekend's game vs. the Cardinals. We'll see how he's listed on the final injury report tomorrow.

49ers WR Brandon Aiyuk (shoulder) was limited in Wednesday's practice. He was seemingly close to playing last Thursday night, so we're tentatively expecting him back for this weekend's game vs. the Cardinals.

49ers WR Brandon Aiyuk (shoulder) is officially inactive for tonight's game vs. the Giants. He seemed relatively close to playing tonight, so we're tentatively expecting him back for Week 4. Aiyuk's absence should make San Francisco's offense even more concentrated, with RB Christian McCaffrey, WR Deebo Samuel, and TE George Kittle dominating touches.

The 49ers have downgraded WR Brandon Aiyuk to out for tonight's game against the Giants because of his shoulder injury. That should make Jauan Jennings the No. 2 WR for the upside matchup. Aiyuk (14) and Deebo Samuel (16) have accounted for 88.2% of WR targets for San Francisco through two weeks, with Jennings claiming the only other four. Jennings posted three games of 4+ receptions last year, though none came with Brock Purdy behind center. Jennings makes for a nice play in Thursday night DFS showdowns. He's too much of a longshot for most season-long redraft formats, though. Seventh-round rookie Ronnie Bell has been the No. 4 WR in playing time so far and matched Jennings in snaps in Week 2. He has yet to see a target, though.