The Cardinals have already ruled WR DeAndre Hopkins (knee) out for this week. Without Hopkins last Sunday, TE Trey McBride and WR Greg Dortch tied for the lead with 25% target share apiece. WR Marquise Brown checked in 1 target behind them. Week 18, however, will find a much tougher defense in San Francisco. Check our Week 18 fantasy football rankings to see where everyone has landed.

Titans WR DeAndre Hopkins (ankle) is listed as questionable for this weekend's game vs. the Browns. He went from a full practice on Wednesday to a limited practice on Thursday and then no practice on Friday. Hopkins said Friday that he'll travel to Cleveland but wouldn't guarantee that he'll play. We'll watch for updates on his status and will get Tennessee's inactives around 11:30 am ET on Sunday. Hopkins managed just four catches for 40 scoreless yards playing through this ankle injury last week.

Titans WR DeAndre Hopkins (ankle) is active for today’s game vs. the Chargers. He didn’t practice all week, so Hopkins obviously carries elevated risk in fantasy lineups. See where he sits in the Week 2 WR Rankings.

Titans WR DeAndre Hopkins (ankle) is expected to play vs. the Chargers today, ESPN's Adam Schefter reports. Hopkins didn't practice all week, so it's safe to assume that he won't be at 100% today. That knocks him down to risk/reward WR3 status, although we haven't heard anything about him being on a snap count today.

Titans WR DeAndre Hopkins (ankle) is listed as questionable for Sunday’s game vs. the Chargers. He didn’t practice all week and was non-committal about his availability when talking to reporters on Friday. Fantasy owners can’t be counting on Hopkins at this point. We’ll look for updates on his status and will get Tennessee’s inactives around 11:30 am ET on Sunday. Hopkins’ absence would open up big opportunity for WR Treylon Burks and TE Chig Okonkwo.

Titans WR DeAndre Hopkins (ankle) missed his second straight practice on Thursday. We haven't heard anything about this ankle issue, so it's possible that Hopkins is just getting some mid-week rest. But check back tomorrow to see how he's listed on the final injury report for this weekend's game vs. the Chargers.