Bills LBs Matt Milano (hamstring) and Tremaine Edmunds (shoulder) are questionable for Sunday's game against the Rams. Each LB put in limited practices all week after missing Week 2. We'll check their statuses Sunday morning.

Bills TE Dawson Knox (concussion) has been ruled out for Sunday's game against the Rams. Tyler Kroft will step in as Buffalo's lead TE but isn't a fantasy option. Knox's absence could mean an extra target or 2 for WRs Stefon Diggs and John Brown.

Bills HC Sean McDermott said during a Friday morning radio interview that RB Zack Moss (toe) will miss Sunday's game against the Rams. That clears the path for Devin Singletary to control backfield touches. Singletary collected just 9 and 10 carries in Buffalo's 1st 2 victories but should see more ground work vs. L.A. He's a fairly comfy RB2 option in an offense that has looked terrific in 2 upside matchups. The Rams bring the toughest defense the Bills will have faced so far.

Bills MLB Tremaine Edmunds (shoulder) and OLB Matt Milano (hamstring) put in limited practices Wednesday and Thursday. Both players missed the Week 2 win at Miami. We'll see if they're ready for this Sunday's game against the Rams. Milano sat out practice all last week, while Edmunds was a limited participant all 3 days. CB Tre'Davious White (shoulder) opened this week limited and wearing a red, non-contact jersey. But he returned to full participation Thursday. DT Ed Oliver (knee) also improved from no practice Wednesday to a limited Thursday. He returned to the Week 2 game after leaving with the knee issue.

Bills RB Zack Moss (toe) remained sidelined for Thursday's practice. He appears to be in real danger of missing this weekend's game vs. the Rams. That'd be a big boost to RB Devin Singletary's projected volume.

Bills RB Zack Moss missed Wednesday's practice with a toe injury. We don't have any further details, but toe injuries can be tough. Let's see if Moss is able to get back on the field tomorrow. His absence would be a big boost for RB Devin Singletary.

Bills TE Dawson Knox was knocked out of Sunday's game in Miami with a concussion. We'll track his progress through the protocol this coming week.

The Bills have ruled out MLB Tremaine Edmunds (shoulder) and OLB Matt Milano (hamstring) for Sunday's game in Miami, according to NFL Network's Ian Rapoport. That elevates strong-side starter A.J. Klein to a full-time role and pushes Tyrel Dodson into Edmunds' starting spot. Each carries sleeper potential for deeper IDP leagues this week.

Bills MLB Tremaine Edmunds (shoulder) put in a limited practice for the 2nd straight day Thursday. We had previously seen him as sitting out Wednesday, but Buffalo's official injury report has Edmunds limited in each practice so far. That's obviously good news for his chances of playing Sunday against Miami. LB Matt Milano, however, missed his 2nd straight practice Thursday with a hamstring injury. Milano looks like he's trending toward missing Week 2. Frankly, he'd look like a risky IDP option even if he makes it back for a limited Friday workout. LB A.J. Klein would likely see full playing time if Milano is inactive.

Bills LBs Tremaine Edmunds (shoulder) and Matt Milano (hamstring) each missed practice Wednesday. Both players left Sunday's win over the Jets early and could be in jeopardy of missing this Sunday's visit to Miami. We'll watch their participation over the next 2 days. A.J. Klein -- the strong-side starter -- and Tyrel Dodson would benefit most in playing time if Edmunds and/or Milano can't go.

Bills MLB Tremaine Edmunds (shoulder) and weak-side LB Matt Milano (hamstring) each left in the 3rd quarter of Sunday's win over the Jets. We'll see about the status of each starter heading into Week 2.

The Bears will start QB Mitchell Trubisky in Week 1 against the Lions, ESPN's Adam Schefter reports. Trubisky and QB Nick Foles seemed to play to a draw in training camp, so Chicago will give its former #2 overall pick one more shot. We're still expecting Foles to start games this season. And this is still a situation to avoid in fantasy drafts.

The Bills on Thursday released K Stephen Hauschka. That means rookie K Tyler Bass appears to have won the job. Make sure you get the appropriate Bills kicker in your fantasy football drafts.

The Bills selected Georgia QB Jake Fromm in the 5th round of the 2020 NFL Draft. Fromm’s tape won’t ‘wow’ you. He’s 6’2, 219 pounds with a below-average arm and bottom-barrel athleticism (22nd percentile SPARQ score). But all he did was win at Georgia. Fromm replaced the injured Jacob Eason early in his 2017 freshman campaign and never relinquished the starting job. He ended up starting 42 games over the past 3 years, compiling a 35-7 record. Fromm leaves the Bulldogs with a career 63% completion rate, 8.4 yards per attempt and 78-to-18 TD:INT ratio. But the fact that he set career lows in completion rate (60.8%) and yards per attempt (7.4) this past season is troubling. Fromm’s 68% adjusted completion rate ranked just 88th among draft-eligible QBs. He’ll battle for the backup job behind Josh Allen in Buffalo.

The 49ers have traded RB Matt Breida to the Dolphins in exchange for a 5th-round pick. Breida has been excellent for the 49ers over the past 3 seasons, averaging 5.0 yards per carry and 8.4 yards per catch. This past year, he ranked 21st in Pro Football Focus' rushing grades among 45 RBs with 100+ carries. Breida was a victim of the numbers game in a packed 49ers backfield but will find plenty of opportunity in Miami, where Jordan Howard resides atop the depth chart. Expect some sort of committee attack in 2020, but Breida's explosiveness and pass-catching ability might make him the more valuable fantasy asset.

The Bills added Central Florida WR Gabriel Davis in the 4th round of the 2020 NFL Draft. Davis was a downfield dynamo last year, averaging 17.2 yards per catch and ranking 4th among all draft-eligible WRs in receptions (16) and yards (620) on targets 20+ yards downfield. There’s not much else to Davis’ game right now — but he just turned 21 earlier this month and goes 6’2, 216 pounds. He’s an intriguing project for the Bills and could eventually replace John Brown, who’s 30 and signed through 2021.

The Bills added Zack Moss to the backfield in the 3rd round of the 2020 NFL Draft. Moss was the Utes’ lead back for his final 3 years on campus, topping 1,000 rushing yards each season and averaging 5.9 yards per carry. That includes career highs in carries (235), yards (1,416) and TDs (15) this past year. Moss was a tackle-breaking machine, ranking 2nd among draft-eligible backs with 89 missed tackles forced and 8th with 1,042 yards after contact, per Pro Football Focus. He’s also good in the passing game, totaling 65 catches for 681 yards (10.5 YPC) and 3 TDs over the past 3 seasons. He ranked 10th in yards per route run among draft-eligible RBs. Moss looks like a subpar athlete on tape, though, and registered a 28th percentile SPARQ score at the Combine. He also carries a lengthy injury history, missing time in college with toe, knee and shoulder issues. We heard one scout compare Moss to a poor man’s Eddie Lacy. He figures to be the ‘thunder’ to Devin Singletary’s ‘lightning’ in Buffalo’s backfield.

The Bills selected Iowa DE A.J. Epenesa in the 2nd round of the NFL Draft. Epenesa delivered strong production in college, with 30.5 tackles for loss and 22 sacks over his 2 seasons as a starter -- plus 6 pass deflections and 8 forced fumbles. But then Epenesa went to the Combine and posted a 40 time that would have been unimpressive for a DT. He looks slow on tape as well, winning on power rather than beating tackles around the edge. Epenesa goes to a well-coached defense in Buffalo, though, and might present the versatility to play some DE and DT. Buffalo signed a similar player in free agency: Quinton Jefferson from Seattle. We're not excited about Epenesa's fantasy outlook, but he'll find a place in dynasty rookie drafts.

Bears GM Ryan Pace has said there's an "open competition" for the team's starting QB job, according to multiple reports. That's not surprising, given the quality of Mitchell Trubisky's play so far and the team's trade for Nick Foles. It's nice to hear the official word, though. We should either get a slight upgrade in Foles or a better-performing Trubisky in the Chicago offense in 2020. Either would mark a welcome change, with some intriguing talent in the skill-position group.

ESPN's Josina Anderson reports that the Saints have agreed to a 2-year deal with WR Emmanuel Sanders. The 33-year-old veteran enters an offense that needs options. Michael Thomas drew a dominating 31.8% of Saints targets last season, nearly doubling #2 Alvin Kamara. Jared Cook ranked 3rd, another 32 targets behind Kamara. There's room for Sanders to rank 2nd among Saints in targets in 2020 and top 100. He's a solid target for best-ball fantasy football drafts now before he climbs into the single-digit rounds.