San Francisco 49ers Fantasy Football News | Shark Bites

49ers QB Brock Purdy suffered a stinger in the fourth quarter of Monday night's game vs. the Ravens. He's been cleared to return, according to ESPN's Lisa Salters, but Purdy has remained on the sidelines with San Francisco trailing by 14. We'll look for more info on Purdy's status, but it sounds like we should expect him to be available for Week 17's game vs. the Commanders.

The Packers have ruled LB De'Vondre Campbell (neck) out for Sunday's game against the Panthers. That pushes Isaiah McDuffie into the starting lineup for what will be his eighth start. McDuffie tallied at least 5 solos in each of those seven previous starts and averaged 9.1 total tackles. He'll be an option for tackle-friendly IDP lineups. McDuffie sits in LB3 territory of our Week 16 rankings. Quay Walker spent the whole practice week limited but carries no injury designation into the game. He should be fine to use. Green Bay also ruled out S Darnell Savage (shoulder).

49ers RB Elijah Mitchell (knee) is out for Sunday’s game vs. the Cardinals. Jordan Mason will again serve as San Francisco’s No. 2 RB – and Christian McCaffrey will continue to dominate backfield work.

The 49ers could be without LB Dre Greenlaw for Sunday's game against the Cardinals. He's questionable with hip and ankle injuries after managing just one limited practice Friday. DC Steve Wilks said Thursday that he expected Greenlaw to play, according to The Athletic's Matt Barrows. CB Charvarius Ward (groin) is also questionable after following the same practice schedule. We'll watch for more on both players over the weekend. The 49ers have ruled out DT Javon Hargrave and DL Arik Armstead.

Niners LB Dre Greenlaw is considered "day-to-day" as he deals with hip and ankle injuries, according to Niners Nation. Greenlaw temporarily left Sunday's win over the Seahawks but played 95% of snaps. He seems like a good bet to be ready for Week 15. DL Arik Armstead "might miss one more game," HC Kyle Shanahan told reporters Monday. DT Javon Hargrave (hamstring) and CB Charvarius Ward (groin) have a "chance" to play. Both left Sunday's game early and did not return. We'll check their statuses through the practice week.

49ers RB Elijah Mitchell (knee) is inactive for today’s game vs. the Seahawks. Jordan Mason will serve as the No. 2 RB, but RB Christian McCaffrey will dominate work – at least as long as this game is still in the balance.

49ers RB Elijah Mitchell (knee) is doubtful for Sunday's game vs. the Seahawks. He's not on the fantasy radar, but his absence can't hurt RB Christian McCaffrey's already massive volume projection.

If you're disappointed in the fantasy output from 49ers LB Dre Greenlaw in Week 13, there's a good explanation. He got ejected midway through the third quarter after an altercation with a security guard on the Eagles' sideline. It doesn't seem as though Greenlaw's likely to face further discipline for the incident. So go back to considering him a potential weekly starter for Week 14 and beyond.

Niners QB Brock Purdy threw for 314 yards and 4 TDs in Sunday's lopsided win at Philadelphia. He hit Brandon Aiyuk, Jauan Jennings, and Deebo Samuel (twice) for scores. It marked the fourth time in the past five games that Purdy threw for at least 296 yards (third game over 300) and the third game among the past four with at least 3 TD passes. Sunday's game marked a rebound from his QB25 fantasy finish in Week 12 against the Seahawks. Purdy gets a rematch with Seattle in Week 14, but we're not downgrading him. Two of the past four QBs to face the Seahawks have thrown 3 TD passes and finished among the top 3 fantasy QBs for the week. After that comes even better matchups with the Cardinals and Commanders in weeks 15 and 17, sandwiching a tough Week 16 spot vs. Baltimore.

Packers LB De'Vondre Campbell (neck) is active for tonight's game against the Chiefs. S Rudy Ford (biceps, groin) and S Darnell Savage (calf) are also active. It'll be Savage's first game since Week 7. CB Jaire Alexander (shoulder) is inactive for the fourth straight game.

Niners WR Deebo Samuel racked up a team-high 9 targets that converted into a 7-79 receiving line Thursday night against the Seahawks. Samuel’s lack of involvement since returning from his multi-week shoulder injury had been a concern (8 combined targets across weeks 10 and 11). Samuel now has four healthy games of 7+ targets, but also four in which he drew 4 targets or fewer. We'd certainly bet on him going higher than 4 targets per game the rest of the way. But Samuel will face weekly volume challenges. The 49ers rank last in the league at 28.1 pass attempts per game and continue to sport WR Brandon Aiyuk, TE George Kittle, and RB Christian McCaffrey. Samuel's remaining schedule ranks second-easiest for WRs per our adjusted fantasy points allowed, which obviously helps. Next week’s matchup vs. the Eagles looks particularly good. The Philly defense ranks fifth in passing yards allowed per game (248.1), and opposing QBs have posted the eighth-best passer rating (96.4) against them this season. The Eagles also play the run much tougher than the pass, which has motivated opponents to pass at the league's second-highest rate over expected. Samuel should sit comfortably inside our top 24 WRs across formats for that matchup. And he's likely to hover in that WR2 range the rest of the way.

Packers LB De'Vondre Campbell (neck) is inactive for today's game against the Lions. He seemed on track to play after putting in a full Wednesday practice. Instead Isaiah McDuffie should start in Campbell's place, next to Quay Walker. Check our updated Week 12 LB rankings.

Packers LB De'Vondre Campbell (neck) returned to a full practice Wednesday after missing the previous two days. Green Bay lists him as questionable for the game, but the betting markets have his tackle lines live. That points to them expecting Campbell to play. We previously removed Campbell from the rankings but have returned him to the Week 12 LB rankings.

Packers LB De'Vondre Campbell left Sunday's win over the Chargers with a stinger. That can be a nerve issue in the shoulder or neck, but it doesn't typically keep a player out long. We'll watch Campbell's status this week. If he misses further time, Isaiah McDuffie would likely fill in.

49ers QB Brock Purdy went off for 333 yards and 3 TDs in Sunday's win over Tampa Bay. He posted a perfect 158.3 QB rating while spreading scores to Brandon Aiyuk, George Kittle, and Christian McCaffrey. Purdy should make his way onto plenty of championship squads, as long as this offense stays healthy. His rest-of-season schedule only includes one negative matchup – Week 16 vs. Baltimore.

Niners HC Kyle Shanahan said after Sunday's game that S Talanoa Hufanga "most likely" suffered an ACL tear in Sunday's win over the Buccaneers. That would obviously end Hufanga's season. Rookie Ji'ayir Brown filled in after Hufanga left and figures to start going forward

49ers WR Deebo Samuel returned from a hairline fracture in his shoulder to post 59 total yards and 1 score vs. Jacksonville. His TD came from 23 yards out on a well-blocked end around. Samuel saw only 4 targets, tied for second on the team behind Christian McCaffrey (10). But he added 3 carries, his average rushing workload on the season. Samuel’s fantasy value figures to fluctuate going forward, as long as both Brandon Aiyuk and George Kittle stay healthy. Still, there’s a clear top-15 ceiling here. San Francisco’s upcoming schedule ranks second best for fantasy WRs.

49ers QB Brock Purdy looked strong in Sunday's win over Jacksonville, throwing for 296 yards and 3 TDs. Purdy had gone three straight games with exactly one TD. On Sunday, though, he spread scores to Brandon Aiyuk, George Kittle, and Kyle Juszczyk, with Kittle’s coming on an impressive deep ball in the face of pressure. Purdy’s strength of schedule looks excellent moving forward, as only one matchup (Week 16, vs. Baltimore) turns up as negative. The nucleus of San Francisco’s offense is healthy, so Purdy will project as a QB1 most weeks.

Niners DT Javon Hargrave (knee) is active for today's game against the Jaguars. Use him as planned in IDP lineups.

49ers WR Deebo Samuel (shoulder) put in a full week of practice and isn’t listed on the final injury report for Sunday’s game vs. the Jaguars. Seemingly healthier than he’s been since Week 2, Samuel is back to WR2-with-upside status.