San Francisco 49ers Fantasy Football News | Shark Bites

The 49ers have designated QB Jimmy Garoppolo to return from IR. That doesn't necessarily mean he'll play again this season; it simply opens the 21-day practice window. With just 2 weeks remaining, that means the team could have Garoppolo practice the rest of the way without needing to decide on activating him. We wouldn't bet on Garoppolo taking the field in Week 16. C.J. Beathard appears in line to face the Cardinals on Saturday.

Update: Cam Inman reports that Garoppolo will practice but "won't play in games." With Nick Mullens set for elbow surgery, Beathard looks like the starter for the final 2 games.

NFL Network's Ian Rapoport reports that 49ers RB Raheem Mostert suffered another high-ankle sprain in Sunday's loss to the Cowboys and is "likely" done for the season. That leaves Jeff Wilson Jr. likely to lead the Week 16 backfield, assuming his own ankle issue doesn't get in the way. Tevin Coleman and Jerick McKinnon sit behind Wilson on the depth chart.

Update: Tom Pelissero reports that the team is placing Mostert on IR.

49ers RB Jeff Wilson appeared to injure his right hamstring late in the loss to Dallas. We’ll update his status when we learn more. Tevin Coleman and Jerick McKinnon are left as San Francisco’s healthy RBs.

49ers RB Raheem Mostert re-injured his left ankle in the 3rd quarter of Sunday's game against the Cowboys. We'll pass along an update when we get one, but it sure looks like Mostert's day is over.

Niners LB Fred Warner (neck, shoulder) and CB Emmanuel Moseley (hamstring) are active for today's game against the Cowboys. Starting outside CB Jason Verrett is a surprise inactive, though, after coming down with an illness. Verrett's absence improves the matchup for Cowboys WRs Michael Gallup and Amari Cooper, who spend most of their time outside.

NFL Network's Ian Rapoport reports that 49ers TE George Kittle (foot fracture) "appears ready to play" in Week 16 after returning to practice this week. But that doesn't necessarily mean Kittle will return. "A lot will go into that decision," a source told Rapoport. At 5-8, San Francisco enters Sunday 2 full games behind Arizona for the final playoff spot in the NFC. A Niners loss and Cardinals win today would eliminate San Francisco from playoff contention, as far as we can tell. That might also keep Kittle from getting back onto the field. We'll see about the TE's status over the coming week. As for QB Jimmy Garoppolo (high-ankle sprain), Rapoport reports he won't play in Week 16 and isn't expected to return for Week 17.

Niners LB Fred Warner (stinger) is questionable for Sunday's game against the Cowboys. He made it back to full practice participation Friday, though. We'll check Warner's status Sunday morning when the inactives come out. CB Emmanuel Moseley (hamstring) is questionable for the game as well. Like Warner, though, he progressed from 2 limited practices to a full Friday. Moseley missed the past 2 games but seems to be trending toward a return. Moseley has been a low-level IDP option most of the year.

49ers RB Raheem Mostert (ankle) put in a full practice on Friday and isn't listed on the final injury report. So he should be ready for his usual role vs. the Cowboys this weekend. Mostert has worked in a committee alongside RB Jeff Wilson the past 3 weeks, leading in carries 39 to 30 but trailing 8 to 7 in targets.

49ers WR Deebo Samuel (hamstring) is out for Sunday’s game against the Cowboys. That leaves Brandon Aiyuk as the #1 WR and a strong target bet. Kendrick Bourne figures to operate as the #2 WR but would be a desperation fantasy play.

49ers RB Raheem Mostert (ankle) returned to a limited practice on Thursday. It gives him a chance to play against the Cowboys this weekend. Check back tomorrow afternoon for another update on his status.

49ers RB Raheem Mostert (ankle) did not practice on Wednesday. We don't have any details on the ankle injury, but he's clearly in some danger of missing this weekend's game vs. Dallas. Mostert's absence would presumably make Jeff Wilson San Francisco's lead back, with Tevin Coleman and Jerick McKinnon candidates for bigger roles.

49ers TE George Kittle (foot) has been activated from IR. NBC Sports' Matt Maiocco reports that Kittle is not expected to play against the Cowboys this Sunday -- but a Week 16 return now looks plausible. We'll keep an eye on the situation, but Kittle is worth a stash if he was dropped in your league.

49ers RB Raheem Mostert came out of Sunday's loss to Washington with an ankle injury, HC Kyle Shanahan said. Mostert was getting additional testing done on Monday, and Shanny said he'd know more about Mostert's status on Wednesday. We'll keep an eye on the situation. Jeff Wilson would seemingly be in line to operate as San Francisco's lead back vs. Dallas this weekend if Mostert is out.

49ers HC Kyle Shanahan said Monday that WR Deebo Samuel will be out "a while" with his latest hamstring injury. With just 2 weeks left in most fantasy seasons, he can be dropped from rosters. WR Brandon Aiyuk is set up to dominate targets the rest of the way. In 4 games without Samuel and TE George Kittle (including last week when Samuel played 1 snap), Aiyuk has caught 24 of 41 targets.

Niners LB Fred Warner left Sunday's loss to Washington in the 3rd quarter. He passed a concussion check, but HC Kyle Shanahan said after the game that Warner sustained a stinger in the neck-shoulder area. We'll see whether that threatens Warner's Week 15 availability.

49ers HC Kyle Shanahan admitted after Sunday's loss to Washington that WR Deebo Samuel's hamstring injury "didn't look good." ESPN's Nick Wagoner tweeted that there's a "real chance" Samuel misses the rest of the season -- although that seems more like speculation than a report. We should get an update on Samuel's status tomorrow. WR Brandon Aiyuk dominated targets in his absence vs. Washington, turning 16 targets into 10 catches for 119 yards.

49ers WR Deebo Samuel injured his hamstring on the 1st drive of Sunday's game against Washington. He's officially questionable to return. Stay tuned for updates.

Niners CB Emmanuel Moseley (hamstring) is questionable for Monday night's game against the Bills. We'll confirm his status when those inactives come out, but the situation probably doesn't make him worth waiting for and trusting in your IDP lineup.

49ers WR Brandon Aiyuk has been activated from the COVID list. That puts him in line to return for Monday night's game against the Bills. San Francisco has had Aiyuk and Deebo Samuel together for only 4 games this season. Samuel has out-targeted Aiyuk 22 to 21 in those contests.

Niners LB Dre Greenlaw (illness) is active for today's game against the Rams. Use him as you normally would in IDP leagues.