The Titans placed QB Ryan Tannehill (ankle) on IR on Thursday. That makes the AFC Championship his earliest possible return this season. We'll see if the Titans roll with QB Malik Willis or QB Joshua Dobbs in next Sunday's must-win game vs. the Jaguars.

As expected, Titans RB Derrick Henry (hip) is inactive for tonight's game vs. the Cowboys. He'd be playing if this game meant anything to Tennessee and will be back out there for the finale against Jacksonville. Rookie Hassan Haskins is expected to operate as Tennessee's lead back tonight but should be considered just a low-upside RB3 in fantasy lineups. The Titans are implied for 13.25 points.

NFL Network's Tom Pelissero has confirmed what we all suspected: that the team "fully" expects RB Derrick Henry to be ready for full use against the Jaguars in Week 18. Henry is doubtful for tonight's game against the Cowboys, listed with a hip issue. But he finished the week with 2 limited practices. He's clearly just being held out of a game that has no bearing on the Titans' playoff hopes. Pelissero added that rookie RB Hassan Haskins is in for a big role and didn't mention RB Julius Chestnut in his report. So Haskins sounds like the guy if you need a Titans runner. We wouldn't go out of our way to target this situation, however, in what Vegas projects to be the lowest-scoring offense of Week 17.

In another clear sign that the Titans are surrendering Thursday night's game to the Cowboys, the team announced Wednesday that basically the entire defense is out or doubtful. DT Jeffery Simmons, S Amani Hooker, EDGE Bud Dupree, LB Dylan Cole and LB Zach Cunningham are out. DL Denico Autry and CB Kristian Fulton are doubtful, which is really just a wishy-washy way of saying "out." LB Monty Rice, CB Roger McCready and S Andrew Adams like just about the only playable pieces for IDP leagues.

The Titans list RB Derrick Henry as doubtful for Thursday night's game against the Cowboys. He has been listed with a hip issue all week but put in limited practices Tuesday and Wednesday after sitting out Monday. This is clearly a move by the Titans to save up some key players for a Week 18 meeting with the Jaguars that will determine whether they make the playoffs. With Henry out and Dontrell Hilliard already on IR, the Titans will turn to Hassan Haskins and Julius Chestnut. With 11 and 5 carries for the season, respectively -- 7 and 2 targets -- neither is a strong bet to grab the clear backfield lead. Try to avoid this offense altogether in your Week 17 fantasy football lineups.

Tennessee's Week 18 game against the Jaguars will determine the AFC South champion. The Titans can't get a Wild Card spot, which makes their game vs. the Cowboys on Thursday night meaningless. Jim Wyatt of the team's official website believe the Titans will hold out some starters out of that one. The big question, of course, is whether that will include RB Derrick Henry. We'll keep you updated on the situation. If Henry is held out, rookie Hassan Haskins would step in as Tennessee's lead back and enter the RB3/Flex conversation.

Titans RB Derrick Henry (hip) was listed as a non-participant at practice on Monday. The Titans are set to face the Cowboys on Thursday night in Week 16. With the quick turnaround, it'll be essential to see Henry log some participation soon. However, this injury didn't seem to affect the veteran on Saturday vs. the Texans. That certainly bodes well for his Week 17 availability. We'll keep an eye on this as we get closer to Thursday.

Cardinals WR DeAndre Hopkins drew 10 targets in Sunday night's OT loss to the Bucs, falling just 1 short of WR Greg Dortch's team lead. But he caught only 1 of them for 4 yards. WR Marquise Brown tallied 3 catches for 57 yards among 6 targets. Third-string QB Trace McSorley averaged just 4.8 yards per attempt on his 45 passes. We'll see whether QB Colt McCoy makes it back for a Week 17 date with the Falcons.

Titans QB Malik Willis went 14-of-23 passing in Saturday's loss to the Texans, tallying just 99 yards (4.3 per attempt) with 0 TDs and 2 INTs. WR Robert Woods was the only Titan with more than 2 receptions, catching all 4 of his targets for 30 yards. Willis will start at least 1 more game Thursday night against the Cowboys.

Titans RB Derrick Henry rushed 23 times for 126 yards and a TD in Saturday's loss to the Texans. That marked a disappointing performance vs. his previous 4 meetings with the Texans, each of which found Henry exceeding 210 rushing yards and scoring at least 2 TDs. But it's tough to complain about the big guy averaging 5.5 yards per rush against a defense that knew he was coming the whole time. Henry boosted that by scoring his TD from 48 yards out, meaning that he averaged 3.5 yards on his other 22 attempts. He gets a tougher matchup with the Cowboys on Thursday night of Week 17.

Titans S Amani Hooker (knee) is inactive for today's game against the Texans.

Titans WR Treylon Burks (concussion) is active for today’s game vs. the Texans. The rookie isn’t a recommended fantasy play with Malik Willis under center.

NFL Network's Ian Rapoport reports that Titans QB Ryan Tannehill had tightrope surgery this week in Alabama to treat his high right ankle sprain. The "best-case scenario" for Tannehill's situation is a 3-week return, which would give him a shot to play in Week 18. We wouldn't bet on him for fantasy football lineups in leagues that play through the final week of the regular season.

Titans WR Treylon Burks (concussion) practiced in full all week. The rookie carries an official injury designation of questionable for Week 16's game vs. the Texans. Hopefully, Burks will clear the concussion protocol and be able to play on Saturday. We'll know more ahead of kickoff regarding his availability.

Titans insider Paul Kuharsky hears that QB Ryan Tannehill is "very likely" done for the season with an ankle injury that may require surgery. Tannehill has hurt this right ankle twice this season -- but was surprisingly allowed to re-enter last week's loss to the Chargers. His absence leaves QB Malik Willis at the controls the rest of the way. The rookie made 2 starts the first time Tannehill went down, TOTALING 135 passing yards on 26 attempts. Tennessee will go as run-heavy as possible with Willis, tanking the fantasy value of pass catchers like TE Chig Okonkwo and WR Treylon Burks.

Titans RB Derrick Henry was listed as a DNP on the injury report on Wednesday with an undisclosed "non-injury related" designation. Henry had been listed as limited on Tuesday, so this is a bit odd. It is hard to give fantasy advice based on this little information. We'll keep you posted as we learn more about this news.

Titans WR Treylon Burks (concussion) practiced fully for the 2nd day in a row on Wednesday. It seems the rookie is likely to play in Week 16's game vs. the Texans on Saturday. Burks has not played since sustaining a head injury in Week 13 vs. the Eagles. With rookie QB Malik Willis likely under center, Burks may not be particularly viable as a fantasy option this week. Additionally, the Texans rank as the 5th-most difficult matchup for WRs in adjusted fantasy points allowed. Burks' potential return to play is better news for Titans fans than fantasy managers.

Titans WR Treylon Burks (concussion) was listed as a full participant at practice on Tuesday. The rookie is trending toward being able to play in Saturday's game vs. the Texans at this rate. It will still be worth monitoring his participation today, however. Fellow rookie TE Chigoziem Okonkwo has stepped up in Burks' absence as a fantasy contributor, so there could be some ripple effects here. We'll keep an eye out.

Per insider Tom Pelissero, Titans QB Ryan Tannehill’s status is “in doubt” for Week 16. Tannehill played through another right ankle injury for parts of Sunday’s game against the Chargers, but it sounds like there’s a real chance he’ll miss Saturday’s matchup with Houston. If so, that’ll put QB Malik Willis back in the lineup vs. the same team he made his debut against in Week 8. The rookie is an easy avoid in season-long formats.

Titans TE Chig Okonkwo led the team in targets (5) in Sunday's loss to the Chargers, catching 4 for 54 yards. He tied RB Derrick Henry for the reception lead and ranked 2nd in yards. The rookie has caught 4+ balls and cracked 50 yards in 3 straight games. He has matched or beaten TE Austin Hooper in targets for 4 weeks in a row.