Rams WR Cooper Kupp has been diagnosed with a high-ankle sprain, ESPN's Adam Schefter reports. A source tells Schefter that it "doesn't sound good." No timetable is given, but high-ankle sprains are generally 4-6 week injuries. So, for now, Kupp owners should brace to be without him until at least Week 15 -- and possibly longer. Kupp leaves behind a massive 30% of Rams targets. Allen Robinson, Van Jefferson, Ben Skowronek and Tyler Higbee should all pick up extra volume, but this Rams passing game could be a disaster with Kupp sidelined.

Rams HC Sean McVay said it's "the hope" that WR Cooper Kupp (hamstring) will be ready to return next week. “He’s progressing. He’s doing a good job," McVay added. "But I don’t want to pigeonhole myself into (anything). He’s ramping up his workload ... When you’re talking about ‘returning to performance’ and ‘returning to play’ those are different things. We want him to be able to ‘return to performance’ at the level he’s capable of, and so we’re continuing to take it a day at a time. I know he’s doing everything in his power to be able to get himself ready to go and get out there with his teammates. Hopefully next week will represent that. If not, I’ll keep you guys posted.” It sounds like Kupp is trending in the right direction -- but isn't necessarily a lock to play next week. We'll keep you updated on the situation.

Rams HC Sean McVay wouldn't put a timeline on WR Cooper Kupp's return when asked on Friday. But he said the Rams are “hopeful” that Kupp will be back when first eligible in Week 5. Kupp remains worth stashing in all fantasy leagues. We'll keep you updated on his status.

The Rams will place WR Cooper Kupp (hamstring) on IR, according to NFL Network's Ian Rapoport. That knocks Kupp out for at least the first four games of the season. Hopefully he's ready to go come Week 5 and the hamstring trouble doesn't resurface. Kupp is certainly worth stashing in all fantasy leagues. Van Jefferson figures to operate as Los Angeles' No. 1 WR with Kupp out. We'll see how the WR corps shakes out behind him. TE Tyler Higbee should also see a bunch of targets sans Kupp.

Rams HC Sean McVay conceded Friday that there's a "definite possibility" that WR Cooper Kupp lands on IR with his hamstring injury. That move would come on Saturday and knock Kupp out for the first four games of the season. It'd be a blow to Kupp's fantasy owners -- but the top priority here should be making sure this hamstring injury is truly behind him before putting him back on the field. Stay tuned.

ESPN's Adam Schefter reported on Wednesday that Rams WR Cooper Kupp (hamstring) has been ruled out for Week 1 vs. the Seahawks. The veteran wideout sustained a setback in rehabbing his hamstring late last week and sought the insight of a specialist in Minnesota on Monday. In speaking on 'NFL Live', Schefter added that Rams HC Sean McVay has not ruled out the possibility that Kupp could be placed on IR. Kupp's absence for Week 1 was a somewhat expected move. The real risk now is that a stint on IR would mean that the fantasy star would miss the first four games of 2023 at a minimum. Managers looking to replace Kupp could look to Van Jefferson, as he's now the presumed Rams WR1. We'll continue to monitor this situation as more information becomes available regarding a potential prolonged absence.