49ers TE George Kittle (knee) put in a full week of practice and isn’t listed on the final injury report. He’ll return for Sunday night’s game against the Eagles and is back to must-start status in fantasy.

49ers QB Jimmy Garoppolo (ankle) is out for Sunday night’s game against the Eagles. QB Nick Mullens gets another start and is on the radar in 2-QB and superflex leagues after chucking for 343 yards and a score last week.

49ers WR Deebo Samuel (foot) will make his 2020 debut against the Eagles on Sunday night. "I know he’ll be out there but it won’t be his normal role, that’s for sure,” HC Kyle Shanahan said. Likely to be on some type of snap count, Samuel isn't a recommended Week 4 fantasy play. But scoop him up if he's available in your fantasy league.

49ers RB Raheem Mostert (knee) remained sidelined for Wednesday's practice. That doesn't bode well for his chances to playing against the Eagles on Sunday night. With Mostert (and Tevin Coleman) out last week, Jerick McKinnon handled 14 carries and 4 targets to Jeff Wilson's 12 carries and 3 targets.

49ers QB Jimmy Garoppolo remained sidelined on Wednesday. That's not a good start in his quest to return for this weekend's game vs. the Eagles. QB Nick Mullens played well in Garoppolo's absence last week, completing 25 of 36 passes for 343 yards, 1 TD and 0 INTs.

49ers TE George Kittle (knee) is a "full go" for Wednesday's practice, HC Kyle Shanahan said. That puts Kittle on track to return for Sunday night's game against the Eagles. An active Kittle remains a must-start in fantasy.

Niners CB Emmanuel Moseley left Sunday's win over the Giants early with a concussion. We'll see whether he has a chance to make it back for the Week 4 Sunday night clash with the Eagles. Dontae Johnson took over Moseley's spot after he departed, finishing with 2 tackles and a pass breakup.

49ers WR Deebo Samuel (foot) is expected to return to practice this coming week and then make his 2020 debut in Week 5 against the Dolphins, according to NFL Network's Ian Rapoport. The Niners have wisely taken it slowly with Samuel's recovery from his Jones Fracture. If he can avoid a setback, he should quickly re-emerge as a weekly fantasy starter. He's worth grabbing now if he's available in your fantasy league.

49ers TE George Kittle (knee) is out for Sunday's game against the Giants. He returned to limited practices this week, so we're betting on a Week 4 return. Jordan Reed, meanwhile, gets another game as San Francisco's lead TE after posting a 7-50-2 line last weekend. It's worth noting that he ran only 20 pass routes in that one, so his floor is lower than we'd like. Consider him a TE2 with upside for Week 3.

49ers TE George Kittle (knee) remained limited in Thursday's practice. NFL Network's Ian Rapoport reported this morning that Kittle has a shot to return for this weekend's game against the Giants. We'll see what he does in tomorrow's practice and then how San Francisco lists him on the final injury report.

49ers TE George Kittle (knee) was limited in Wednesday's practice. That's an upgrade from last week, when Kittle didn't practice at all. Check back tomorrow for another update on his progress.

Niners DE Dee Ford is expected to miss his 2nd straight game Sunday, according to NFL Network's Tom Pelissero. The injury was listed as a neck issue for Week 2, which Ford missed. Pelissero reports it as a back injury that needs to "settle down" and "may take some time." Ford has spent a lot of time dealing with various ailments since joining the 49ers last offseason. He's fine to dump in most IDP redraft leagues until this current injury "settles." The injuries to both him and DE Nick Bosa leaves room for new 49er Ezekiel Ansah and DE Kerry Hyder to see plenty of snaps.

The MRI has confirmed that 49ers DE Nick Bosa tore his left ACL in Sunday's win over the Jets. So his season's done. It's also the 2nd ACL tear of his football career. Bosa previously tore his right ACL in high school. That at least means Bosa has been through the process. We'll see about his progress during the offseason. The Niners, meanwhile, agreed to a 1-year deal with DE Ezekiel Ansah to help fill the void.

49ers HC Kyle Shanahan conceded Monday that RB Raheem Mostert (knee) "likely won't play" vs. the Giants this weekend. Mostert is reportedly dealing with a minor MCL sprain, so this shouldn't be a long-term absence. But it's looking like the 'Niners will be down to RBs Jerick McKinnon and Jeff Wilson for at least Week 3. Both guys are worth scooping off waiver wires.

Niners HC Kyle Shanahan says QB Jimmy Garoppolo's high-ankle sprain isn't serious, according to multiple reports. The team considers Garoppolo week to week, and he might have a shot to play the Giants this Sunday. We'll see how the week goes for Garoppolo. Nick Mullens would start if Garoppolo misses further time.

The 49ers believe RB Raheem Mostert is dealing with a "mild sprain of the MCL," according to ESPN's Adam Schefter. It's relatively good news. The severity of the sprain will determine how long Mostert is sidelined. We should learn more tomorrow.

49ers QB Jimmy Garoppolo has been diagnosed with a high-ankle sprain, ESPN's Adam Schefter reports. Garoppolo was able to play through the injury during the 1st half of the win over the Jets before sitting out the 2nd. Skill guys tend to miss multiple games with this injury, but perhaps the QB can return for Week 3. If not, San Francisco will turn to QB Nick Mullens, who completed 8 of 11 passes for 71 yards and a score in relief of Garoppolo today. In 8 starts back in 2018, Mullens averaged 285 yards and 1.6 TDs per game.

Niners DE Nick Bosa left in the 1st quarter of Sunday's game against the Jets with a left knee injury. The team ruled him out for the day in the 2nd quarter. We'll see about the severity, as Bosa is likely headed for a Monday MRI.

Update: HC Kyle Shanahan said after the game that it's "most likely an ACL," according to NBC Sports' Matt Maiocco. That probably means a tear. We'll await Monday confirmation, but that would be a big blow to San Francisco's defense.

49ers RB Raheem Mostert suffered a knee injury in the 1st half of Sunday's game against the Jets and is done for the day. That leaves San Francisco with RBs Tevin Coleman and Jerick McKinnon.

49ers QB Jimmy Garoppolo suffered a right ankle injury in the 1st half of Sunday's game against the Jets. He finished that half but will not play in the 2nd, the team announced. This might be a case of San Francisco playing it safe with a 21-3 lead. We'll look for updates on Garoppolo's status after the game. QB Nick Mullens is in for the 49ers.