49ers RB Jeff Wilson (calf) is listed as questionable for Sunday’s game against the Patriots after a limited week of practice. With Raheem Mostert and Tevin Coleman out, Wilson’s absence would leave San Francisco with only RBs Jerick McKinnon and JaMycal Hasty.

The Panthers have placed K Joey Slye on the COVID list. He'll likely miss Sunday's game against the Saints. We'll see who Carolina signs to kick this weekend, but plan on avoiding the situation in Week 7 fantasy lineups.

Niners RB Raheem Mostert sustained a high-ankle sprain in Sunday night's win over the Rams and is headed to IR, according to Grant Cohn of SI.com. That means he'll miss at least 3 games. We'll see beyond that. Jerick McKinnon is the guy we know will be involved in replacing Mostert for Sunday's game at New England. He garnered just 8 touches for 28 total yards against the Rams, though. Jeff Wilson missed Week 6 with a calf injury he suffered during the practice week. That left rookie JaMycal Hasty working in his place against the Rams. Tevin Coleman is eligible to come off IR for Week 7, but we don't yet know whether his sprained knee will be ready. We'll see how this backfield picture develops through the week.

Niners RB Raheem Mostert left Sunday night's game against the Rams with a left ankle injury. The team ruled him out for the rest of the game, which isn't great news for his Week 7 outlook. We'll watch for further updates on his status. If Mostert misses further time, Jerick McKinnon and Jeff Wilson would step back to prominence. Tevin Coleman should also be nearing a return from the knee sprain that has kept him from playing since Week 2.

49ers RB Jeff Wilson (calf) is inactive for tonight's game against the Rams. He played 23% of the offensive snaps and handled 4 carries with 1 target last week, so his absence opens up a little more work for RBs Raheem Mostert and Jerick McKinnon.

Niners CB Emmanuel Moseley (concussion) is questionable for Sunday's game against the Rams. He finished the week with 2 full practices, though, and looks on track to play. We'll confirm Moseley's status Sunday.

49ers QB Jimmy Garoppolo (ankle) will start Sunday night’s game against the Rams, HC Kyle Shanahan said on Friday. Garoppolo reportedly had a good week of practice after his disastrous half vs. the Dolphins. Make Garoppolo earn his way back into your fantasy lineup after that dud.

49ers HC Kyle Shanahan said he pulled QB Jimmy Garoppolo from this past week's game against Miami because his injured ankle was impacting his play. Shanny wouldn't say whether Garoppolo will be able to start this weekend's game vs. the Rams. "We'll see how he is on Wednesday," Shanahan said. "I expect him to be at least the same, if not better. So, hopefully we can get a week of that and have no setbacks (on) Wednesday, Thursday and Friday. And hopefully we get him out there Sunday night." We'll track Garoppolo's status, but plan on avoiding the 49ers QB situation in Week 6 fantasy lineups.

49ers QB Jimmy Garoppolo was benched at halftime of Sunday's game against Miami. He was horrible in the first 30 minutes, completing just 7 of 17 passes for 77 yards and 2 INTs. QB C.J. Beathard replaced Garoppolo. We're assuming the 'Niners will go back to Garoppolo next week, but we'll see what HC Kyle Shanahan says.

49ers WR Deebo Samuel (illness) is active for today’s game against the Dolphins. We’re expecting him to play more than the 34% of snaps he did last week, although he still might not be ready for a full workload. Consider Samuel a WR3 in today’s plus matchup.

49ers RB Raheem Mostert (knee) is active for today’s game against the Dolphins. He missed the last 2 games and was limited in practice this week, so it’s unclear how big a role he’s ready for. It leaves Mostert as a risk/reward Week 5 fantasy play.

49ers RB Raheem Mostert (knee) and WR Deebo Samuel (illness) are expected to play against the Dolphins today, ESPN's Adam Schefter reports. Mostert has been sidelined since Week 2 and was limited in practice all week, so it's unclear how big a role he's ready for. Samuel played just 34% of San Francisco's offensive snaps in his 2020 debut last week. He should be ready for more this afternoon -- although missing practice on Thursday and Friday with that illness might impact that plan.

The 49ers have ruled CB Emmanuel Moseley (concussion), CB Dontae Johnson (groin) and CB K'Waun Williams (knee, hip) out for Sunday's game against the Dolphins. CB Ahkello Witherspoon (hamstring) is also questionable. He missed last week's game against the Eagles but managed limited workouts this week. We'll check on Witherspoon's status Sunday, though he's not much of an IDP factor either way. The big takeaway here is that the Niners will miss at least 4 of their top 6 corners -- with Richard Sherman still on IR. That can only help Miami QB Ryan Fitzpatrick, WR DeVante Parker and TE Mike Gesicki.

49ers WR Deebo Samuel is listed as questionable for this weekend’s game against the Dolphins after missing practice on Thursday and Friday with a non-COVID illness. Guys almost always play through this stuff, but we’ll look for an update on Samuel on Sunday morning.

49ers RB Raheem Mostert (knee) was limited in practice all week and is listed as questionable for Sunday’s game against the Dolphins. HC Kyle Shanahan suggested Friday that Mostert will be a game-time decision. That means we might not know his status until 3 pm ET on Sunday. Jerick McKinnon will be a high-end RB2 if Mostert remains out; a RB3/Flex play if Mostert suits up.

49ers QB Jimmy Garoppolo (ankle) will return for Sunday's game against the Dolphins, HC Kyle Shanahan said. Garoppolo is a significant upgrade for San Francisco's pass-catchers and is a high-upside QB2 in this matchup. The 'Niners are implied for 29.25 points -- 6th highest on the week.

49ers RB Raheem Mostert (knee) put in a limited practice on Wednesday. It gives him a shot to return for this weekend's game against the Dolphins. When healthy, Mostert figures to be the lead back in a committee alongside Jerick McKinnon.

49ers QB Jimmy Garoppolo put in a limited practice on Wednesday, his 1st since suffering a high-ankle sprain back in Week 2. It gives him a chance to return for this weekend's game against the Dolphins. We'll see how Garoppolo trends over the next couple of days.

The 49ers have ruled CB Emmanuel Moseley out for Sunday night's game against the Eagles with a concussion. The team has also ruled CB Ahkello Witherspoon out (hamstring) and deemed slot CB K'Waun Williams questionable. With Richard Sherman already out, San Francisco will be missing at least 3 of its top 4 corners for the game. The question, of course, is whether the banged-up Philly offense can exploit that weakness.

49ers RB Raheem Mostert (knee) is out for Sunday night’s game against the Eagles. He didn’t practice all week and isn’t a lock to be back for Week 5. Jerick McKinnon figures to operate as San Francisco’s lead back vs. Philly, with Jeff Wilson also getting plenty of action.