49ers RB Ty Davis-Price (ankle) is not listed on the final injury report and will be available for Sunday’s game vs. the Falcons. Assuming the rookie is active, he figures to be 3rd on the depth chart behind RBs Jeff Wilson and Tevin Coleman.

49ers RB Ty Davis-Price (ankle) put in a full practice on Wednesday. It looks like he's ready to return from his Week 2 high-ankle sprain. The rookie figures to slot in 3rd on the depth chart for now, behind RBs Jeff Wilson and Tevin Coleman.

49ers WR Brandon Aiyuk snagged 3 of 4 targets for 58 yards in Sunday's win over Carolina. The 3rd-year WR is now at a ho hum 18.6% target share in 3 full games alongside Jimmy Garoppolo. Despite some big-play juice, Aiyuk figures to remain a hot-and-cold WR3 for the foreseeable future. Week 6 turns up a road matchup with Atlanta.

Niners HC Kyle Shanahan says EDGE Nick Bosa has a groin strain, according to ESPN's Nick Wagoner. He'll be re-evaluated Wednesday, we assume to determine whether Bosa will be ready to practice and/or play this week. We'll watch for further updates, but it continues to sound like a minor injury.

49ers TE George Kittle showed progress with 5 catches for 47 yards in Week 5 at Carolina. He made a few impressive contested catches, although he did lose one fumble. His 6 targets ranked 2nd on the team and represented a decent 20% team share. The veteran entered Sunday with only 50 yards on 6 catches across his first 2 appearances. A low-volume passing game will keep the volatility high going forward, but we’re still likely to see some spike weeks soon. Week 6 turns up a positive scoring matchup at Atlanta.

49ers WR Deebo Samuel mustered only 2 catches for 20 yards in Week 5. He added a score, but the story here was strong coverage from CB Jaycee Horn, who eventually departed in the 3rd quarter with a hip injury. Samuel handled only 2 carries (for 12 yards) and witnessed a sharp decline in his backfield snaps. Starting in Week 1, his RB snaps have gone: 9, 11, 8, 8, 1. Samuel will look for more in a positive Week 6 matchup at Atlanta.

The Panthers fired HC Matt Rhule. His former team is sitting at 1-4 after going 10-23 over his first 2 seasons. Carolina's ranks in total yards: 21st, 30th and 32nd. Defensive Pass Game Coordinator/Secondary Coach Steve Wilks will take over as interim HC, according to NFL Network's Ian Rapoport. He was HC for the Cardinals' 3-13 2018 season. It sounds like OC Ben McAdoo will be sticking around. We're not expecting the change to help Carolina's floundering offense (although it can't hurt).

Niners EDGE Nick Bosa left at halftime of Sunday's win over the Panthers with a groin issue. Here's what HC Kyle Shanahan said afterward, according to ESPN.com: "He started feeling it, it was a little tight all day. In the 2nd quarter, you could see him coming off the field. We looked into it at halftime -- he didn't feel like he could go." The team expects to test the injury further on Monday, but it doesn't sound like it's believed to be serious. We'll watch for updates.

The 49ers have ruled DE Arik Armstead (foot, ankle) and DT Javon Kinlaw (knee) out for Sunday's game against the Panthers. That damages both the run D and pass rush for San Francisco. We'll see, though, whether the Carolina offense can take advantage. We'd still feel comfy using the Niners' team D in fantasy football lineups.

49ers WR Deebo Samuel tallied 6 catches for 115 yards and 1 score in Week 4. He was nearly shutout on the ground (2 carries, 2 yards) but made his night with a 57-yard TD where he broke several tackles. Going back to 2021, Samuel’s now scored 5 TDs of 40+ yards. Next up is a road matchup with Carolina.

49ers TE George Kittle managed only 24 yards on 2 catches in a Week 4 win over the Rams. His 4 targets tied for 2nd on the team and represented a lackluster 14.8% share. Kittle nearly scored, but he couldn’t quite get his 2nd foot down in bounds. So, we’re looking at 2 duds in 2 appearances for the veteran. He at least ran a route on ~86% of Jimmy Garoppolo’s dropbacks — but clearly, we’re headed for volatility with the run-heavy 49ers.

Niners DL Arik Armstead left Monday night's game against the Rams with a foot injury. He has been dealing with plantar fasciitis. We'll see about his status for Week 5.

Panthers RB Christian McCaffrey entered Sunday questionable with a thigh injury he had to test pregame. But he wound up with normal playing time and 17 of the 18 RB opportunities for Carolina in the loss to the Cardinals. McCaffrey managed only 27 yards on 8 rushes but caught all 9 of his targets for 81 yards and a TD. D'Onta Foreman got the only other RB touch: a 2-yard run. He played 4 snaps to Chuba Hubbard's 3.

Panthers QB Sam Darnold (ankle) is eligible to come off the IR this week but is expected to still be sidelined for "a while," a source tells ESPN's Adam Schefter. This is worth reporting because QB Baker Mayfield has been so bad through 4 games that we're all wondering whether Darnold might actually be an upgrade. Unfortunately, it looks like it'll be Mayfield for at least a few more games.

Panthers RB Christian McCaffrey (thigh) is active for today’s game vs. the Cardinals. He carries elevated risk after getting in just a limited practice on Friday. But if you were waiting on him, get McCaffrey into your fantasy lineup.

ESPN's Jeremy Fowler hears that the Panthers are "optimistic" about RB Christian McCaffrey's availability for today's game vs. the Cardinals but that he'll need to test that injured quad in pre-game warmups before a final decision is made. "One key in that test will be going full speed, which he didn’t do much of in practices," Fowler adds. Cardinals-Panthers kicks off at 4:05 pm ET, so we won't get Carolina's inactives until a little after 2:30.

ESPN's Adam Schefter calls Panthers RB Christian McCaffrey (thigh) "likely" to play vs. the Cardinals today. "He might not be at full strength" after missing 2 practices this week, Schefter adds. We'll look for further updates on the situation, but unless we hear that McCaffrey's snaps and touches will be significantly scaled back, he belongs in Week 4 fantasy lineups.

49ers RB Ty Davis-Price (ankle), as expected, has been ruled out for Monday night's game vs. the Rams. RB Jeff Wilson played 73% of the offensive snaps, handled 12 of 13 RB carries and saw 3 targets last week and figures to play a similar role on Monday night.

The Panthers list RB Christian McCaffrey as questionable with the quad injury that has limited his activity this week. McCaffrey did take part in Friday's practice. We'll have to watch his status through the weekend.

Panthers RB Christian McCaffrey (quad) missed practice again on Thursday. NFL Network's Ian Rapoport hears, though, that "there is still optimism that he plays" vs. the Cardinals this weekend. "He’s kept it close to the vest, but barring a setback he should be OK," Rapoport adds. We'll get another update on CMC tomorrow.