49ers WR Deebo Samuel (hamstring) was limited on Thursday for the 2nd straight practice. We'll see what he does on Friday and how he's listed on the final injury report for this weekend's game vs. the Saints.

49ers WR Deebo Samuel (hamstring) was limited in Wednesday's practice. He missed Week 8 with a hamstring injury, although it's unclear if this is related. We'll get another update on Samuel tomorrow.

The Panthers announced Tuesday that QB Sam Darnold will start Sunday's game against the Broncos. Darnold himself will be far from a real fantasy-lineup option for that matchup, and we're not sure he improves the outlook for the offense on whole. But a move away from Baker Mayfield can't be bad for D.J. Moore's target shares. Moore drew 27.2% of Panthers targets in the 11 games Darnold started last season. He has garnered just 22.6% target share in Mayfield's 5 starts this year.

49ers HC Kyle Shanahan said after Sunday night's win over the Chargers that he was “hoping that the carries could come out about even" between RBs Christian McCaffrey and Elijah Mitchell. Mitchell ended up out-carrying McCaffrey 18 to 14, receiving 5 of the final 6 carries because, as Shanahan said, "we were just feeling him." This obviously isn't what McCaffrey owners want to hear, but don't panic. Even if he's truly going to split carries 50/50 with Mitchell, there's enough to go around for McCaffrey to still settle in somewhere around 12-15 carries per game. And, of course, he'll dominate passing-game work. He's racked up 15 targets on a massive 28% share over San Francisco's last 2 games. It's a similar role to Austin Ekeler's -- and he currently leads all RBs in PPR points per game.

Niners WR Brandon Aiyuk drew a team-high 7 targets in Sunday night's win over the Chargers, also leading the team in receptions (6) and receiving yards (84). WR Deebo Samuel trailed by just 1 target but caught only 2 passes for 24 yards. Samuel hasn't beaten Aiyuk in targets since Week 5. TE George Kittle managed just 1 reception for 21 yards among 2 targets. WR Jahan Jennings caught all 4 of his looks for 40 yards. The 49ers head to Mexico City next Monday night to face the Cardinals.

RB Elijah Mitchell led the 49ers in carries Sunday night in his 1st action since a Week 1 knee injury. He carried 18 times for 89 yards, beating Christian McCaffrey by 4 attempts and 51 yards. McCaffrey claimed the lone TD between them and caught 4 of 6 targets to add 39 yards. Mitchell drew 2 targets and caught 1 for a loss of a yard. We'll see about this backfield plan going forward. But the even split in Mitchell's return sets McCaffrey up as a "sell-high" candidate in redraft leagues.

Officials ejected 49ers LB Dre Greenlaw late in the 2nd quarter of Sunday night's game against the Chargers after a hit to the head of Chargers QB Justin Herbert. We wouldn't bet on any league suspension accompanying this, so Greenlaw should be set to return next Monday night at Arizona.

Niners LB Dre Greenlaw (calf) has been cleared to play Sunday night against the Chargers. Greenlaw hasn't played since Week 7, so it's tough to know if he's ready for a full snap allotment. But he'll carry upside if he does. The Chargers have supplied the 5th most fantasy points per game to LBs so far this season.

49ers WR Deebo Samuel (hamstring) put in a full week of practice and isn’t listed on the final injury report. He’ll be ready for a full workload vs. the Chargers on Sunday night.

49ers RB Elijah Mitchell (knee) will be activated from IR and play vs. the Chargers on Sunday night, HC Kyle Shanahan said. Mitchell has been out since going down with a sprained MCL in the season opener. He figures to return as the #2 RB behind Christian McCaffrey. Mitchell is unlikely to hold standalone fantasy value but is worth rostering as the CMC handcuff.

The 49ers got LB Dre Greenlaw (calf) back for a limited practice Wednesday. He missed the last game (Week 8) with the injury that knocked him out of the loss to the Chiefs. We'll watch to see whether he's ready to return to the lineup this Sunday against the Chargers. DL Arik Armstead (foot, ankle) remained out Wednesday, which doesn't bode well for his chances of playing for the 1st time since Week 4. EDGE Samson Ebukam (quad, Achilles') also didn't practice.

Niners WR Deebo Samuel was a full participant at Wednesday's practice. He missed Week 8 with a hamstring injury but looks ready to face the Chargers coming out of the bye week. He should be back in your fantasy football lineups and sits inside the top 20 in our Week 10 fantasy football rankings.

Niners DL Arik Armstead said Monday his return to action is "coming soon," according to NBC Sports Bay Area. Armstead revealed that he has been recovering from a hairline fracture in his left ankle. That plus plantar fasciitis in his left foot have kept him out since Week 4. We'll see whether Armstead is ready for Sunday's game against the Chargers.

49ers WR Deebo Samuel (hamstring) was on the field for Monday's post-bye-week practice, according to ESPN's Nick Wagoner. That seemingly puts Samuel on track to return for Sunday night's game vs. the Chargers. We'll get San Francisco's first official practice report of the week on Wednesday.

49ers RB Elijah Mitchell (knee) has been designated to return from IR. He's now eligible to practice and be placed on the active roster whenever ready. Mitchell has been sidelined since going down with a sprained MCL in the season opener. While he was out, of course, San Francisco traded for RB Christian McCaffrey. So Mitchell will return as the #2 RB -- and just a handcuff in fantasy football. We'll see if he's ready to play vs. the Chargers on Sunday night.

The Panthers activated QB Sam Darnold (ankle) from IR. He's been practicing for a couple of weeks but is now evidently ready for game action. We'll see who Carolina goes with at QB vs. the Falcons this weekend. QB P.J. Walker was benched at halftime of the loss to the Bengals. QB Baker Mayfield played his best football of the season over the 2nd half, completing 14 of 20 passes for 155 yards, 2 TDs and 0 INTs.

Niners WR Brandon Aiyuk caught all 6 of his targets in Sunday's win over the Rams. He tallied 81 yards and caught a TD throw from RB Christian McCaffrey. San Francisco went without WR Deebo Samuel. McCaffrey led the team in targets and receptions, with TE George Kittle (5 targets) following McCaffrey and Aiyuk. QB Jimmy Garoppolo completed 21 of 25 passes (84%) for 235 yards and TDs to McCaffrey and Kittle.

Niners RB Christian McCaffrey accounted for TDs running, receiving and even passing in Sunday's win over the Rams. He posed an 18-94-1 rushing line, claiming 81.8% of San Francisco's RB carries. He also led the 49ers in targets (9) and receptions (8), ranked 2nd in receiving yards (55) and snagged 1 of QB Jimmy Garoppolo's 2 TD throws. McCaffrey also hit WR Brandon Aiyuk for a score from 34 yards out early in the 2nd quarter. McCaffrey dominated backfield work in his 2nd appearance with the team. San Francisco gets a Week 9 bye and then plays at home 4 of the next 5 games.

49ers WR Jauan Jennings (hamstring) is inactive for today’s game vs. the Rams. He joins WR Deebo Samuel on the sidelines for this one, leaving WRs Ray-Ray McCloud, Danny Gray and Willie Snead behind Brandon Aiyuk.

The 49ers have ruled LB Dre Greenlaw (calf) and DL Arik Armstead (foot, ankle) out for Sunday's game against the Rams. Demetrius Flannigan-Fowles looks like the fill-in for Greenlaw. Armstead will be missing his 4th straight game.