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Chargers LB Denzel Perryman is questionable for Sunday's opener against the Colts because of an ankle injury. He put in limited practices all week, which would suggest he's a decent bet to play. Perryman hasn't been an every-snap LB even when healthy though and makes for just a middling IDP option. LB Jatavis Brown is doubtful for the game after missing practice all week with his own ankle injury. It's not clear how much that matters, though. The team website lists Thomas Davis and Uchenna Nwosu as starters next to MLB Perryman. Various injuries have kept us from being able to confirm that via preseason action. This is a situation to avoid for now in most IDP leagues.

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Chargers DE Joey Bosa (ankle) and S Nasir Adderley (ankle) are questionable for Sunday's game against the Vikings. HC Brandon Staley said he expects Bosa to play, despite missing Friday's practice with his injury. Adderley is expected to be a game-time decision. We'll update the status for each ahead of the 4:05 p.m. ET kickoff.

The Chargers have ruled LB Drue Tranquill out for Sunday's game at Baltimore with a chest injury. S Nasir Adderley is questionable with a hip injury. We'll update his status Sunday morning. Tranquill's absence should make Kyzir White a good bet to lead Chargers LBs in playing time and tackles.

The Chargers held practice Wednesday without EDGE Joey Bosa (foot, ankle) and S Derwin James (toe). James played every defensive snap in Sunday's loss to the Cowboys, and Bosa matched his Week 1 allotment (82%), so we're guessing neither is a serious issue. But we'll watch their participation levels through the week.

Chargers CB Chris Harris Jr. is out for Sunday's game against the Cowboys with a shoulder injury. That leaves L.A. without its top cover man and primary slot corner. Dallas WR Cedrick Wilson likely stands to benefit the most. With Michael Gallup out, Wilson will serve as the #3 wideout and played 85% of his pass snaps in the slot in Week 1.

The Chargers have named Brandon Staley their new HC. The 38-year-old has been a fast riser, going from a LBs coach in Chicago and Denver to Rams defensive coordinator to Chargers HC in just 5 years. Staley's 2020 Rams defense was better than Wade Phillips' 2019 unit in points allowed, total yards allowed, yards per play allowed and Football Outsiders' DVOA. This at least looks like a good hire for the Chargers defense. We'll see who joins Staley to run the offense.

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