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49ers WR Deebo Samuel (hamstring) is out for Sunday’s game against the Cowboys. That leaves Brandon Aiyuk as the #1 WR and a strong target bet. Kendrick Bourne figures to operate as the #2 WR but would be a desperation fantasy play.

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HC Kyle Shanahan said the 49ers expect WR Deebo Samuel to miss 1-2 weeks with the groin strain he suffered in Sunday's win over the vikings, according to ESPN's Adam Schefter. That leaves Brandon Aiyuk to lead the WR corps for the next game or 2, with Jauan Jennings and Trent Sherfield likely to each see more time. Samuel's absence can only help George Kittle's target outlook as well.

49ers WR Deebo Samuel is expected to miss "a little time" with the groin injury he suffered in Sunday's win over the Vikings, according to NFL Network's Ian Rapoport. But "it’s not considered a major injury," Rapoport adds. We'll look for more details on the situation, but it sounds like fantasy owners should at least plan on being without Deebo in Week 13.

49ers WR Deebo Samuel injured his groin in the 3rd quarter of Sunday's game vs. the Vikings. He's officially questionable to return. Stay tuned for an update.

Buffalo
3:00pm EST 11/7/21

49ers WR Deebo Samuel (calf) is active for today’s game against the Cardinals. He was listed as questionable after getting in limited practices on Thursday and Friday. ESPN’s Adam Schefter reported this morning that the ‘Niners are “uncertain how long” Samuel will be able to play through the calf issue. Consider him a risk/reward WR2 in Week 9 fantasy lineups.

49ers WR Deebo Samuel (calf) is listed as questionable for Sunday’s game against the Cardinals after getting in limited practices on Thursday and Friday. Samuel played through the calf injury last week, but HC Kyle Shanahan said Friday that it’s worse now. Samuel is expected to play on Sunday, but he’ll carry elevated risk in fantasy lineups.

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