49ers QB Jimmy Garoppolo (ankle) is out for Sunday night’s game against the Eagles. QB Nick Mullens gets another start and is on the radar in 2-QB and superflex leagues after chucking for 343 yards and a score last week.

49ers QB Jimmy Garoppolo (calf) is off the final injury report and will start Sunday night's game against the Colts. QB Trey Lance has been ruled out with his knee injury, so he won't vulture any snaps from Garoppolo.

49ers QB Trey Lance (knee) did not practice on Monday. QB Jimmy Garoppolo (calf) was out there and looked good according to media members in attendance. At this point, bank on Garoppolo starting this weekend's game against the Colts. That'd be good news for WR Deebo Samuel.

49ers HC Kyle Shanahan said Tuesday that he expects QB Jimmy Garoppolo (calf) to be ready coming out of the Week 6 bye. “I mean, he’s doing good,” Shanahan said. “We’ll see when we get back [after the bye week]. I think he’ll be ready to go next week when we get back. That’s the plan. I know he’s doing a lot better now than he was last week.” Shanahan has consistently said that a healthy Garoppolo remains his starter. And, frankly, QB Trey Lance didn't play well enough in last week's loss to the Cardinals to change that.

49ers QB Jimmy Garoppolo (calf) is out for Sunday’s game against the Cardinals. He’ll get a Week 6 bye to heal up. But QB Trey Lance gets his 1st career start this weekend. He’s been shaky as a passer in the preseason and the 2nd half of last week’s game. But his high-end rushing ability gives him QB1 upside.

49ers QB Jimmy Garoppolo (calf) missed practice again on Thursday. It continues to look like QB Trey Lance will get his 1st career start vs. Arizona this weekend. We'll see if Garoppolo can get on the practice field tomorrow.