49ers QB Jimmy Garoppolo has been diagnosed with a high-ankle sprain, ESPN's Adam Schefter reports. Garoppolo was able to play through the injury during the 1st half of the win over the Jets before sitting out the 2nd. Skill guys tend to miss multiple games with this injury, but perhaps the QB can return for Week 3. If not, San Francisco will turn to QB Nick Mullens, who completed 8 of 11 passes for 71 yards and a score in relief of Garoppolo today. In 8 starts back in 2018, Mullens averaged 285 yards and 1.6 TDs per game.

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The 49ers swung a massive trade for the #3 overall pick in next month's draft, sending the #12 pick, a 2021 3rd-rounder and 1st-rounders in 2022 and 2023 to the Dolphins. The 'Niners clearly have their eyes on a QB. ESPN's Adam Schefter hears that the team doesn't have 1 specific rookie in mind but is "good with the options" that will be available. That'll be some combination of BYU's Zach Wilson, Ohio State's Justin Fields and North Dakota State's Trey Lance. Schefter also reports that San Francisco "has no plans" to trade QB Jimmy Garoppolo -- but his days as the starter are clearly numbered. The Dolphins, meanwhile, are reaffirming their commitment to QB Tua Tagovailoa with this trade.

The 49ers have designated QB Jimmy Garoppolo to return from IR. That doesn't necessarily mean he'll play again this season; it simply opens the 21-day practice window. With just 2 weeks remaining, that means the team could have Garoppolo practice the rest of the way without needing to decide on activating him. We wouldn't bet on Garoppolo taking the field in Week 16. C.J. Beathard appears in line to face the Cardinals on Saturday.

Update: Cam Inman reports that Garoppolo will practice but "won't play in games." With Nick Mullens set for elbow surgery, Beathard looks like the starter for the final 2 games.

ESPN's Adam Schefter reports that 49ers QB Jimmy Garoppolo is expected to miss at least the next 6 weeks with what has been deemed a high-ankle injury. The QB could remain out even longer if his injury winds up requiring surgery, according to Schefter. Garoppolo obviously doesn't belong on any redraft fantasy football rosters during this span. QB Nick Mullens is in play for deeper leagues, including 2-QB and superflex formats. We'll see, though, whether he can hold the job. C.J. Beathard relieved Mullens in the Week 4 loss to Philadelphia and then Garoppolo in the following week's loss to the Dolphins.

49ers QB Jimmy Garoppolo was pulled in the 4th quarter of Sunday's game against the Seahawks. He appeared to tweak his knee or ankle taking a sack on his final snap and headed back to the locker room with trainers. Garoppolo was horrible before exiting, throwing for 84 yards, 0 TDs and 1 INT against a leaky Seattle defense. We'll see if Garoppolo is healthy enough to start Thursday night's game vs. the Packers -- and if San Francisco sticks with him.

Update: The 49ers announced Garoppolo with an ankle injury.

49ers QB Jimmy Garoppolo (ankle) will start Sunday night’s game against the Rams, HC Kyle Shanahan said on Friday. Garoppolo reportedly had a good week of practice after his disastrous half vs. the Dolphins. Make Garoppolo earn his way back into your fantasy lineup after that dud.

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