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49ers QB Jimmy Garoppolo has been diagnosed with a high-ankle sprain, ESPN's Adam Schefter reports. Garoppolo was able to play through the injury during the 1st half of the win over the Jets before sitting out the 2nd. Skill guys tend to miss multiple games with this injury, but perhaps the QB can return for Week 3. If not, San Francisco will turn to QB Nick Mullens, who completed 8 of 11 passes for 71 yards and a score in relief of Garoppolo today. In 8 starts back in 2018, Mullens averaged 285 yards and 1.6 TDs per game.

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After a non-committal press conference on Sunday, 49ers HC Kyle Shanahan named QB Jimmy Garoppolo his Week 8 starter on Monday. "We didn't go into that game thinking that Jimmy was one bad game away from losing his job or anything like that," Shanahan explained. "Jimmy didn't play as good as he could, which he knows that and I know that. I think there were some pretty hard circumstances for him -- for both quarterbacks, considering some of the weather. But I definitely thought he could play better." QB Trey Lance (knee) is expected to practice on Wednesday, so he'll presumably be available for this weekend's game vs. the Bears. But it'll be in a gadget role, not as the starter.

49ers HC Kyle Shanahan was rather unenthusiastic when asked whether QB Jimmy Garoppolo will remain his starter in Week 8. “I would guess so," Shanahan said. "We had two QBs hurting this week. Jimmy was able to come back and play. We'll see if Trey [Lance] can next week, we're still not sure yet, but I got a lot of things to figure out.” Garoppolo mustered just 181 passing yards with 1 TD and 2 INTs in Sunday night's loss to the Colts -- although, in his defense, the game was played in messy weather. Regardless, expect to see Lance back under center for San Francisco at some point this season. We'll see when rookie is ready to return from his knee injury.

49ers QB Jimmy Garoppolo (calf) is off the final injury report and will start Sunday night's game against the Colts. QB Trey Lance has been ruled out with his knee injury, so he won't vulture any snaps from Garoppolo.

49ers QB Trey Lance (knee) did not practice on Monday. QB Jimmy Garoppolo (calf) was out there and looked good according to media members in attendance. At this point, bank on Garoppolo starting this weekend's game against the Colts. That'd be good news for WR Deebo Samuel.

49ers HC Kyle Shanahan said Tuesday that he expects QB Jimmy Garoppolo (calf) to be ready coming out of the Week 6 bye. “I mean, he’s doing good,” Shanahan said. “We’ll see when we get back [after the bye week]. I think he’ll be ready to go next week when we get back. That’s the plan. I know he’s doing a lot better now than he was last week.” Shanahan has consistently said that a healthy Garoppolo remains his starter. And, frankly, QB Trey Lance didn't play well enough in last week's loss to the Cardinals to change that.

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