49ers HC Kyle Shanahan admitted after Sunday's loss to Washington that WR Deebo Samuel's hamstring injury "didn't look good." ESPN's Nick Wagoner tweeted that there's a "real chance" Samuel misses the rest of the season -- although that seems more like speculation than a report. We should get an update on Samuel's status tomorrow. WR Brandon Aiyuk dominated targets in his absence vs. Washington, turning 16 targets into 10 catches for 119 yards.

Niners WR Deebo Samuel racked up a team-high 9 targets that converted into a 7-79 receiving line Thursday night against the Seahawks. Samuel’s lack of involvement since returning from his multi-week shoulder injury had been a concern (8 combined targets across weeks 10 and 11). Samuel now has four healthy games of 7+ targets, but also four in which he drew 4 targets or fewer. We'd certainly bet on him going higher than 4 targets per game the rest of the way. But Samuel will face weekly volume challenges. The 49ers rank last in the league at 28.1 pass attempts per game and continue to sport WR Brandon Aiyuk, TE George Kittle, and RB Christian McCaffrey. Samuel's remaining schedule ranks second-easiest for WRs per our adjusted fantasy points allowed, which obviously helps. Next week’s matchup vs. the Eagles looks particularly good. The Philly defense ranks fifth in passing yards allowed per game (248.1), and opposing QBs have posted the eighth-best passer rating (96.4) against them this season. The Eagles also play the run much tougher than the pass, which has motivated opponents to pass at the league's second-highest rate over expected. Samuel should sit comfortably inside our top 24 WRs across formats for that matchup. And he's likely to hover in that WR2 range the rest of the way.

49ers WR Deebo Samuel returned from a hairline fracture in his shoulder to post 59 total yards and 1 score vs. Jacksonville. His TD came from 23 yards out on a well-blocked end around. Samuel saw only 4 targets, tied for second on the team behind Christian McCaffrey (10). But he added 3 carries, his average rushing workload on the season. Samuel’s fantasy value figures to fluctuate going forward, as long as both Brandon Aiyuk and George Kittle stay healthy. Still, there’s a clear top-15 ceiling here. San Francisco’s upcoming schedule ranks second best for fantasy WRs.

49ers WR Deebo Samuel (shoulder) put in a full week of practice and isn’t listed on the final injury report for Sunday’s game vs. the Jaguars. Seemingly healthier than he’s been since Week 2, Samuel is back to WR2-with-upside status.

49ers WR Deebo Samuel (shoulder) was a full participant in Wednesday's practice. It's confirmation that he's on track to return for this weekend's game vs. the Jaguars' 23rd-ranked WR defense. See where Samuel sits in the Week 10 WR Rankings.

When asked about his shoulder injury on the "Up & Adams" show on Thursday, 49ers WR Deebo Samuel said, "I'm ready to go." It sounds like we can expect Samuel to play vs. the Jaguars in Week 10, following San Francisco's Week 9 bye. We'll monitor his practice participation next week.