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The 49ers traded up to select Ohio State RB Trey Sermon with the 88th overall pick of the 2021 NFL Draft. Sermon opened his college career solidly at Oklahoma, averaging 5.9 yards per rush and scoring 20 total TDs over his 1st 2 seasons. But he fell out of favor with the coaching staff there before transferring to Ohio State for his final season. Sermon spent most of 2020 splitting touches with Master Teague but closed out the year with a 29-331-2 rushing line in the Big Ten championship game win over Northwestern and then a 31-193-1 outing in the semifinal win over Clemson. Sermon brings enough size (6’0, 215), tested well athletically and put a nice blend of running skills on his college tape. There’s 3-down upside to his game, though he’s more likely headed for some level of backfield share in San Francisco alongside Raheem Mostert and Jeff Wilson. It’s a strong running game under HC Kyle Shanahan, though, so this is a nice landing spot.

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49ers RB Trey Sermon will "lead the way" and get the "bulk of carries" vs. the Packers tonight, according to NFL Network's Mike Garafolo. We've heard the same from multiple 49ers beat writers. Sermon isn't the safest Week 3 fantasy play -- but he has loads of upside in a plus matchup.

49ers RB Trey Sermon (concussion) has been medically cleared and isn't listed on the final injury report. With RB JaMycal Hasty (ankle) out and RB Elijah Mitchell (shoulder) doubtful, it's currently Sermon, Trenton Cannon and Jacques Patrick at RB on San Francisco's active roster. RBs Kerryon Johnson and Chris Thompson are eligible to be activated from the practice squad. HC Kyle Shanahan wouldn't say Friday afternoon who will get the start vs. Green Bay, but multiple 49ers beat writers expect it to be Sermon. We'll continue to look for clues on how the touches will be divvied.

49ers RB Trey Sermon (concussion) remained limited in Thursday's practice. He still has multiple stages of the protocol to clear if he's to play vs. the Packers on Sunday night. We'll get another update on his progress tomorrow.

49ers RB Trey Sermon (concussion) got in a limited practice on Wednesday. It means that he's made some progress through the league's protocol. If Sermon can get cleared in time for Sunday night's game vs. the Packers, the 49ers might be forced to give him a significant role.

49ers HC Kyle Shanahan confirmed on Monday that RB Trey Sermon sustained a concussion in the win over the Eagles. It happened on Sermon's 1st carry of the game, which didn't come until the 4th quarter. We'll see when the rookie is cleared, but he's a ways away from fantasy relevance right now.

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