49ers QB Brock Purdy went 25/34 for 295 yards and 5 TDs with RB Christian McCaffrey going 21-117-0 on the ground and 6-29-2 on 8 targets through the air. The 49ers team put up 48 points on the Colts with Purdy tossing every TD except a late fourth-quarter pick-six from the defense. The 49ers' offense helped elevate playoff fantasy teams to make comebacks and could be league winners next week against the Bears.

49ers TE George Kittle hurt his left ankle in the third quarter of Monday night's game vs. the Colts. He was visibly frustrated as he made his way off the field. Kittle was deemed questionable to return and remained on the sidelines, but he never made it back onto the field. He had a monster game before exiting, catching 7 of 8 targets for 115 yards and a score. But his availability for Sunday night's game vs. the Bears is now uncertain. HC Kyle Shanahan didn't have an update on the injury afterward. We'll keep you posted.

The NFL is suspending Steelers WR DK Metcalf two games for "initiating a physical confrontation with a fan" amid Sunday's win over the Lions. Metcalf is appealing the suspension, according to NFL Network's Tom Pelissero.

Ravens QB Lamar Jackson has a "serious contusion" to his back and is considered "day to day," HC John Harbaugh said Monday. "It doesn't look like it's more than that," Harbaugh added. "He's in there getting treatment now." We'll keep tabs on Jackson's status, but we're tentatively expecting him to play vs. the Packers on Saturday night. Still, fantasy managers should make sure to have a replacement plan rostered in case Jackson can't go.

Chargers RB Kimani Vidal is considered "day to day" with a neck strain suffered in the Week 16 win over the Cowboys, according to NFL Network's Ian Rapoport. "Vidal could miss time, but the belief is that it's not serious," Rapoport adds. We'll start the week projecting Vidal to miss Saturday's game vs. the Texans, which would leave Hassan Haskins as the No. 2 RB and likely mean a significant boost in volume for RB Omarion Hampton.

Chiefs QB Gardner Minshew left the game against the Titans with a knee injury. Despite some fears of a torn ACL, tests showed that Minshew's ACL is in tact. He is still expected to miss time and not return this season. Ian Rapoport reports that the injury is specifcally a bad bone bruise, non-displaced tibial plateau fracture. Minshew was placed on IR. With Minshew missing the season, the Chiefs have signed QB Shane Buechele from the Bills' practice squad. He spent the 2021 and 2022 seasons with the Chiefs.

Bengals RB Chase Brown racked up 109 total yards and three scores in Sunday's blowout win over Miami. Brown became the first RB with three TDs in a quarter since Joe Mixon did it with the Bengals in 2022. In total, Brown's 32.9 PPR points topped his prior season-high by nearly eight.

Browns TE Harold Fannin Jr. caught 4 of 6 targets for 34 yards and one score in Sunday's loss to the Bills. The rookie added a goal line rushing TD.

Bills TE Dalton Kincaid was held without a catch in Sunday’s close win over the Browns. Kincaid drew only one target on a day that saw Josh Allen throw for 130 yards on 12-of-19 passing.

Jaguars WR Parker Washington racked up 6 catches for 145 yards and a TD in Sunday's decisive win over the Broncos. He led the team in catches, yards, and targets (10) despite ranking just fourth in pass routes. Washington's 70.5% route rate trailed WR Jakobi Meyers (95.5%), WR Brian Thomas Jr. (84.1%), and TE Brenton Strange (72.7%).

Browns RB Quinshon Judkins is expected to be sidelined for 4-5 months with the dislocated ankle and fractured fibula he suffered in Sunday's loss to the Bills, according to NFL Network's Ian Rapoport. That timeline would put Judkins back on the field in April or May. He'll miss part of the offseason program, but it sounds like he'll be ready for the start of training camp. The injury ultimately shouldn't have much of an impact on his 2026 outlook. Although the efficiency wasn't great this year (3.6 yards per carry), Judkins flashed more than enough -- coupled with his second-round draft capital -- to be a heavy favorite to open next season as Cleveland's lead back.

The Ravens were forced to play most of Week 16 without QB Lamar Jackson, who injured his back in the second quarter. Baltimore RB Derrick Henry did his part, rushing for 128 yards and 2 TDs, but it wasn't enough as the Patriots reeled off 15 unanswered points in the fourth quarter to defeat the Ravens 28-24. Henry's performance was his best showing since opening the season with 169 yard and a pair of TDs against the Bills.

Patriots RB TreVeyon Henderson banged his head on the turf while being tackled on a 1-yard run in the second quarter and was evaluated for a concussion. Henderson was ruled out of the game mid-way through the third quarter. Rhamondre Stevenson filled in for the rest of the game for the Patriots, who rallied in the fourth quarter to defeat the Ravens 28-24. Henderson was held to 3 yards on 5 carries and caught a pass for 9 yards before he exited the game. He will have to clear the league's concussion protocol before he can return to action. If Henderson misses Week 17, Stevenson would be on the RB2 radar against a New York Jets' defense that has allowed the third-most fantasy points to RBs. We'll keep an eye on Henderson's progression through the protocol and his participation in practice this week.

Baltimore Ravens QB Lamar Jackson suffered a back injury in the second quarter of the team's 28-24 loss. Jackson was kneed in the lower left side with 1:56 remaining in the second quarter and headed to the locker room early. Tyler Huntley came in to finish that drive and played the entire second half as Jackson dealt with the injury. An MRI scheduled for Monday should tell us more. If Jackson can't play, Tyler Huntley would get the start in Week 17 in a crucial matchup against the Packers. UPDATE: Jackson is day-to-day with a back bruise.

WR Tetairoa McMillan went 6-73-1 on 10 targets against the Buccaneers. Jalen Coker was the next highest WR with 5 targets. McMillan matched up against CB Jamel Dean often who had been stout against outside WRs, but McMillan was able to win multiple times one-on-one. As the Panthers march toward the NFC South crown, McMillan has proved himself to be an elite option who can be relied upon for the fantasy championship (and next season).

With QB Patrick Mahomes out for the season after tearing his ACL and WR Rashee Rice missing this week with a concussion, the Chiefs offense struggled against a poor Titans’ defense. QB Gardner Minshew left the game with a knee injury in the second quarter forcing the team to turn to QB Chris Oladokun. The team only scored 6 points* for the remainder of the game.

The Steelers backfield has been a question mark all season with RB Jaylen Warren starting and having the primary rushing role but Kenneth Gainwell’s pass catching and blocking getting him plenty of work. Both paid off for fantasy managers this week. Warren went 14-143-2 on the ground and 2-8-0 through the air on 2 targets. Gainwell went 9-50-0 on the ground and 5-78-1 through the air on 7 targets. Gainwell’s TD came on an incredible catch at the end of the first half.

Broncos WR Troy Franklin tallied a fairly unimpactful 4-66 receiving line in Sunday's loss to the Jaguars. The numbers get even less impressive when you consider that Bo Nix attempted 47 passes in a game his team trailed from the middle of the third quarter on.

Jaguars QB Trevor Lawrence threw for 279 yards and 3 TDs in Sunday's win over the Broncos. He added 20 yards on the ground, including a 1-yard TD plunge.

Cowboys WR George Pickens racked up 7 catches for 130 yards and a TD in Sunday's win over the Chargers. He led the team in receptions, yardage, and targets (nine). That game followed two straight weeks of 37 receiving yards or less and came against a well-performing Chargers' pass D.