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The 49ers on Tuesday deemed DE Nick Bosa "week-to-week" with a muscle strain in his upper right leg. HC Kyle Shanahan said Bosa was preparing to play through it before an MRI revealed the strain. It doesn't seem like an issue that should threaten Bosa's start to the regular season, though we'll keep an eye on his situation. Bosa missed most of August last season with a hamstring injury, which sounds like the area holding him back now as well. That -- plus a September ankle sprain -- didn't stop him from registering an impressive rookie. DE Dee Ford is also out with a calf "irritation," but the team lists him as merely "day-to-day."

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Asked about DE Nick Bosa on Tuesday, 49ers HC Kyle Shanahan said, "We fully expect him to be ready for training camp." Bosa tore his left ACL in Week 2, but it sounds like rehab has gone well. This is his 2nd time going through the process -- the 1st came back in high school -- and Shanahan spoke highly of Bosa's setup (away from the team). Shanahan also this week related Bosa's impact on the defense to those of Aaron Donald and Von Miller to their respective teams. So it's clear the coach is excited to get his defensive playmaker back. We'll certainly keep an eye on the potential top-5 IDP lineman throughout the summer.

The MRI has confirmed that 49ers DE Nick Bosa tore his left ACL in Sunday's win over the Jets. So his season's done. It's also the 2nd ACL tear of his football career. Bosa previously tore his right ACL in high school. That at least means Bosa has been through the process. We'll see about his progress during the offseason. The Niners, meanwhile, agreed to a 1-year deal with DE Ezekiel Ansah to help fill the void.

Buffalo
3:09pm EDT 9/20/20

Niners DE Nick Bosa left in the 1st quarter of Sunday's game against the Jets with a left knee injury. The team ruled him out for the day in the 2nd quarter. We'll see about the severity, as Bosa is likely headed for a Monday MRI.

Update: HC Kyle Shanahan said after the game that it's "most likely an ACL," according to NBC Sports' Matt Maiocco. That probably means a tear. We'll await Monday confirmation, but that would be a big blow to San Francisco's defense.

Niners DE Nick Bosa (ankle) is active for today's game against the Bengals. He had some soreness in his previously sprained ankle coming out of Week 1 and got some rest from practice during the week. But Bosa also graded out tops among all edge players in Pro Football Focus' pass-rushing productivity in Week 1. He's worth the risk against a Bengals offense that looks weak in pass protection.

Niners rookie DE Nick Bosa is questionable for Sunday's game at Cincinnati. Bosa came away from Week 1 with some soreness in his previously sprained ankle, GM John Lynch said during a radio interview Friday. Bosa sat out Wednesday's and Thursday's practices before returning to limited participation Friday. Lynch said Bosa was progressing well. We'll see if he's ready to go. There will be some re-injury risk even if he plays but also enticing sack upside.

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